Results 201 to 210 of about 15,663 (264)

Aluminium adjuvants in vaccines and potential health effects: systematic review.

open access: yesBMJ
Doyon-Plourde P   +6 more
europepmc   +1 more source
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Lithium as an immunologic adjuvant

Medical Hypotheses, 1980
Lithium, an adenylate cyclase inhibitor, stimulates a variety of in vitro indices of immune function, including proliferation of lymphocytes in response to mitogens, rosette formation by T-cells and phagocytosis by macrophages. Lithium enhances these immunologic responses at concentrations comparable to those achieved in patients receiving lithium for ...
L, Shenkman, W, Borkowsky, B, Shopsin
openaire   +2 more sources

DDA as an immunological adjuvant

Research in Immunology, 1992
As compared to other adjuvants, DDA is a moderate or strong adjuvant for humoral responses and a strong adjuvant for CMI, especially DTH responses, against different types of antigens and in both laboratory animals and larger animals. DDA can collaborate with other immunomodulating compounds resulting in further enhanced responses.
L A, Hilgers, H, Snippe
openaire   +2 more sources

Comparison of immunological adjuvants

APMIS, 2019
In this study, several innate immunological adjuvants and related compounds were compared with respect to complement activation in serum and induction of cytokine release in whole blood samples using immunoassays. As found, simple lipids had no effect on the complement system or on cytokine release, whereas lipopolysaccharides induced prominent release
Nicole H, Trier   +5 more
openaire   +2 more sources

Cytokines as immunological adjuvants

Vaccine, 1992
Various cytokines have been shown to be effective immunological adjuvants in a variety of model systems, enhancing protection induced by viral, bacterial and parasitic vaccines, and increasing parameters of immunity in tumour immunization models and in clinical trials.
A W, Heath, J H, Playfair
openaire   +2 more sources

Recombinant cytokines as immunological adjuvants

Immunology & Cell Biology, 1993
SummaryThis paper describes the bacterial expression and purification of bioactive recombinant ovine interleukin‐2 (rovIL‐2), interleukin‐lα (rovlL‐lα) and tumour necrosis factor α. These purified proteins had specific activities in appropriate bioassays of 1 × 107, 1 times; 107 and 1 × 105 U/mg, respectively.
Nash, AD   +7 more
openaire   +5 more sources

Current Status of Immunological Adjuvants

Annual Review of Immunology, 1986
Sixty years ago Ramon demonstrated that it was possible to augment the antitoxin response to diphtheria and tetanus by administering vaccines with pyogenic bacteria or with various additional compounds (1). Since that time, clinicians and immunologists have sought to potentiate the immune response with adjuvants while attempting to minimize the often ...
H S, Warren, F R, Vogel, L A, Chedid
openaire   +3 more sources

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