Results 181 to 190 of about 21,995 (302)

A modular nanoparticle display strategy for varicella-zoster virus gE based on a licensed protein scaffold. [PDF]

PLoS Pathog
Xue W, Wang H, Zeng Y, Zhang S, Cui L, Liu H, Li H, Hong M, Zhang H, Zhang Y, Li J, Chen Z, Zheng Q, Yu H, Zhu R, Zhou L, Gu Y, Li T, Xia N, Li S.   +19 more
europepmc   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Recent developments in cancer immuno-interception strategies. [PDF]

Trends Mol Med
Zhu Z, Mathew J, Barrett B, Wang HH, Huff AL, Armstrong TD, Jaffee EM, Zaidi N.   +7 more
europepmc   +1 more source

Lung Ultrasound for the Detection of Radiologic Progression of Interstitial Lung Abnormalities in Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Interstitial lung disease (ILD) is an important extra‐articular manifestation of rheumatoid arthritis (RA) associated with high mortality and morbidity. Lung ultrasonography (LUS) has recently emerged as a possible screening tool. We assessed the role of LUS in monitoring radiologic progression and the development of new interstitial lung ...
Marie Vermant, Valerie Van Ballaer, Joseph Jacob, Tine Follet, Ryoko Egashira, Kenny Anseele, Heleen Cypers, Laurens J. De Sadeleer, Nico De Crem, Tinne Goos, Barbara Neerinckx, Veerle Taelman, Nathalie Veyt, Alexandros Kalkanis, Patrick Verschueren, Wim A. Wuyts   +15 more
wiley   +1 more source

Application of a small molecule calcium influx inducer as a vaccine adjuvant: enhancing Th2-biased immune responses. [PDF]

Front Immunol
Yokoyama Y, Sako Y, Yao S, Gil F, Cozza R, Jin J, Mclaughlin I, Anguiano Quiroz P, Brown T, Shukla NM, Chan M, Corr M, Carson DA, Hayashi T.   +13 more
europepmc   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Immunogenicity of subunit vaccine of E2 protein against atypical porcine pestivirus in pigs. [PDF]

Front Cell Infect Microbiol
Huang Y, Guo L, Chen L, Yin L, Yuan P, Zhao Y.   +5 more
europepmc   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Pharmaceutical formulations as immunological adjuvants [PDF]

The aim of this work was to enhance the immune responses to ovalbumin (OVA) following its oral administration, by the association of the protein with colloidal carriers, which may protect the protein from degradation in the gastrointestinal tract and/or facilitate its uptake across the intestine.
openaire  

Importance of Vaccine Adjuvants: A Comparative Study of Antibody Acquisition Rates and Levels Before and After Adjuvant Change in the Hepatitis B Vaccine. [PDF]

Intern Med
Yoneyama K, Kurihara T, Tsuboya A, Yamamura F, Okajima Y, Tanaka D.   +5 more
europepmc   +1 more source