Results 241 to 250 of about 21,384 (315)

Novel nanoemulsion adjuvant stabilized by TPGS possesses equivalent physicochemical properties, Turbiscan stability, and adjuvanticity to AS03 for eliciting robust immunogenicity of subunit vaccines in mice. [PDF]

Hum Vaccin Immunother
Yin Q, Song S, Liu Z.
europepmc   +1 more source

Targeting the ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti‐VEGF resistance in endometrial cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) in endometrial cancer (EC) progression and its potential as a therapeutic target to enhance the efficacy of antiangiogenic treatment. Methods ST3Gal1 expression and its clinical relevance were analyzed in EC tissues.
Chia‐Hao Liu, Szu‐Ting Yang, Wei‐Ting Chao, Chen‐Hao Lin, Yu‐Chieh Lee, Chiung‐Ru Lai, Shie‐Liang Hsieh, Liang‐Wei Wang, Peng‐Hui Wang   +8 more
wiley   +1 more source

Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development. [PDF]

Front Immunol
Alrasheed AR, Awadalla M, Alnajran H, Alammash MH, Almaqati AM, Qadri I, Alosaimi B.   +6 more
europepmc   +1 more source

Development of an Enzymatic Recombinase Amplification Assay for the Rapid Detection of Plasmodium Nucleic Acids

iLABMED, EarlyView.
The detection rate of enzymatic recombinase amplification (ERA) was better than that of the rapid diagnostic test. The ERA assay was more convenient than fluorescence quantitative PCR. The ERA assay can be used as a complementary tool for malaria screening and clinical diagnosis.
Xinxin Yang, Xiaoxue Lu, Junlian Yang, Wen Xu, Qian Li, Weiwei Chen   +5 more
wiley   +1 more source

Characterizing TLR4 agonist EmT4™ as an anti-Mycobacterium tuberculosis vaccine adjuvant. [PDF]

Immunohorizons
Larsen SE, Rais M, Reese VA, Ferede D, Pecor T, Kaur S, Nag D, Smytheman T, Gray SA, Carter D, Baldwin SL, Coler RN.   +11 more
europepmc   +1 more source

Investigation on Klebsiella pneumoniae in the field of extracellular vesicles

Interdisciplinary Medicine, EarlyView.
The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu, Yuheng Liu, Jin Su, Yi Yang, Haiyi Deng, Yilin Yang, Mengxi Yanglan, Xinyi Wu, Shiqi Luo, Yao Liao, Lifu Wang   +10 more
wiley   +1 more source

Combination adjuvant improves influenza virus immunity by downregulation of immune homeostasis genes in lymphocytes. [PDF]

Immunohorizons
Dollinger E, Hernandez-Davies J, Felgner J, Jain A, Hwang M, Strahsburger E, Nakajima R, Jasinskas A, Nie Q, Pone EJ, Othy S, Davies DH.   +11 more
europepmc   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Nucleic acid vaccines: innovations, efficacy, and applications in at-risk populations. [PDF]

Front Immunol
Konopka EN, Edgerton AO, Kutzler MA.
europepmc   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source