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Adjuvants

Veterinary Immunology and Immunopathology, 1987
A number of adjuvants of importance in veterinary vaccines are reviewed. These include mineral salt adjuvants, oil adjuvants, hydrophilic and hydrophobic bloc polymers, hydrocarbons and surface active agents. The current and future applications of these substances and their possible modes of action are discussed. Creation of an adjuvant register by the
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Adjuvants and autoimmunity

Lupus, 2009
Some adjuvants may exert adverse effects upon injection or, on the other hand, may not trigger a full immunological reaction. The mechanisms underlying adjuvant adverse effects are under renewed scrutiny because of the enormous implications for vaccine development.
E, Israeli   +3 more
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Adjuvant castration versus adjuvant chemotherapy

International Journal of Radiation Oncology*Biology*Physics, 1978
Furthermore, in premenopausal women under 45 years of age Meakin et al.” failed to observe a significant difference in terms of delay of recurrence and prolongation of survival between those who had radical mastectomy (RM) and RM plus ovarian irradiation (RT). Since histologically positive axillary lymph nodes were identified in 87% (RM) and in 98% (RT)
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Genetic Adjuvants

2003
In 1992, the era of DNA vaccines began with the report of antibody production upon intradermal injection of mice with a plasmid vector expressing a foreign antigen (1). A rapid succession of subsequent manuscripts showed stimulation of immune responses, including cytolytic T cells, upon inoculation of expression-vectors specific for antigens derived ...
H C, Ertl   +10 more
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The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine

Vaccine, 2001
Elderly people and subjects with underlying chronic diseases are at increased risk for influenza and related complications. Conventional influenza vaccines provide only limited protection in the elderly population. In order to enhance the immune response to influenza vaccines, several adjuvants have been evaluated. Among these, an oil in water adjuvant
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Adjuvant Analgesics

Medical Clinics of North America, 2007
Adjuvant analgesics represent a diverse group of drugs that were originally developed for a primary indication other than pain. Many of these medications are currently used to enhance analgesia under specific circumstances. The proper use of adjuvant drugs is one of the keys to success in effective pain management.
Helena, Knotkova, Marco, Pappagallo
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Vaccine Adjuvants

Clinical Infectious Diseases, 1980
Nonreplicating, purified subunit or synthetic viral vaccines of the future are likely to be weak immunogens that will require immunopotentiation if they are to be effective. These marginal vaccines could be improved by combination with potent and safe immunologic adjuvants. The use of adjuvants should also reduce the amount of purified antigen required
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Mechanisms of adjuvancy: I?metal oxides as adjuvants

Vaccine, 1997
The exact mechanism of how immune adjuvants function still remains largely unknown, despite their long history of use. This work reports the properties of alum and the related compounds Al(OH)3 or Al2O3. Experiments were performed in rats to determine the relative adjuvancy of silica, talc, ground glass, Al2O3, SnO2, ZrO2, hematite and magnetite ...
J O, Naim   +4 more
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Vaccine adjuvants

Seminars in Veterinary Medicine and Surgery: Small Animal, 1997
Vaccine adjuvants provide enhanced immune responses to a variety of antigens. Unlike human vaccines that are limited to aluminum-based adjuvants, veterinary vaccines may contain a large number of substances either alone or in combination that act as vaccine adjuvants.
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Immunological adjuvants IV. Relationship between adjuvant activity and antigenicity in mycobacterial adjuvant

Experientia, 1971
Wahrend sich bei Endotoxinen der Adjuvanseffekt proportional zur Antigenitat verhalt, ist diese Beziehung bei dem aus Tuberkelbazillen isolierten Wachs D nicht der Fall.
T, Ishibashi   +3 more
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