Results 281 to 290 of about 157,049 (314)
Some of the next articles are maybe not open access.
Mechanisms of adjuvancy: I?metal oxides as adjuvants
Vaccine, 1997The exact mechanism of how immune adjuvants function still remains largely unknown, despite their long history of use. This work reports the properties of alum and the related compounds Al(OH)3 or Al2O3. Experiments were performed in rats to determine the relative adjuvancy of silica, talc, ground glass, Al2O3, SnO2, ZrO2, hematite and magnetite ...
C. J. van Oss +4 more
openaire +3 more sources
International Journal of Immunopharmacology, 1994
T-cell adjuvancy involves the use of agents to stimulate preferentially delayed type hypersensitivity (DTH). Traditional adjuvants like Alum, Freunds, muramyl peptides, and endotoxins are not selective. Natural infection (e.g. vaccinia) may yield selective DTH. Low dose cyclophosphamide (CY) with mycobacteria was the first experimental T-cell adjuvant.
openaire +3 more sources
T-cell adjuvancy involves the use of agents to stimulate preferentially delayed type hypersensitivity (DTH). Traditional adjuvants like Alum, Freunds, muramyl peptides, and endotoxins are not selective. Natural infection (e.g. vaccinia) may yield selective DTH. Low dose cyclophosphamide (CY) with mycobacteria was the first experimental T-cell adjuvant.
openaire +3 more sources
The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine
Vaccine, 2001Elderly people and subjects with underlying chronic diseases are at increased risk for influenza and related complications. Conventional influenza vaccines provide only limited protection in the elderly population. In order to enhance the immune response to influenza vaccines, several adjuvants have been evaluated. Among these, an oil in water adjuvant
openaire +3 more sources
Experientia, 1971
Wahrend sich bei Endotoxinen der Adjuvanseffekt proportional zur Antigenitat verhalt, ist diese Beziehung bei dem aus Tuberkelbazillen isolierten Wachs D nicht der Fall.
Tatsuro Ishibashi +3 more
openaire +3 more sources
Wahrend sich bei Endotoxinen der Adjuvanseffekt proportional zur Antigenitat verhalt, ist diese Beziehung bei dem aus Tuberkelbazillen isolierten Wachs D nicht der Fall.
Tatsuro Ishibashi +3 more
openaire +3 more sources
Adjuvant synergy: The effects of nasal coadministration of adjuvants
Immunology & Cell Biology, 2004Modern peptide and protein subunit vaccines suffer from poor immunogenicity and require the use of adjuvants. However, none of the currently licensed adjuvants can elicit cell‐mediated immunity or are suitable for mucosal immunization. In this study we explored the immunological effect of nasal co‐administration of adjuvants with distinct functions ...
Sterghios Moschos +3 more
openaire +3 more sources
Clinical Infectious Diseases, 1980
Nonreplicating, purified subunit or synthetic viral vaccines of the future are likely to be weak immunogens that will require immunopotentiation if they are to be effective. These marginal vaccines could be improved by combination with potent and safe immunologic adjuvants. The use of adjuvants should also reduce the amount of purified antigen required
openaire +2 more sources
Nonreplicating, purified subunit or synthetic viral vaccines of the future are likely to be weak immunogens that will require immunopotentiation if they are to be effective. These marginal vaccines could be improved by combination with potent and safe immunologic adjuvants. The use of adjuvants should also reduce the amount of purified antigen required
openaire +2 more sources
Seminars in Veterinary Medicine and Surgery: Small Animal, 1997
Vaccine adjuvants provide enhanced immune responses to a variety of antigens. Unlike human vaccines that are limited to aluminum-based adjuvants, veterinary vaccines may contain a large number of substances either alone or in combination that act as vaccine adjuvants.
openaire +2 more sources
Vaccine adjuvants provide enhanced immune responses to a variety of antigens. Unlike human vaccines that are limited to aluminum-based adjuvants, veterinary vaccines may contain a large number of substances either alone or in combination that act as vaccine adjuvants.
openaire +2 more sources
Emerging concepts in the science of vaccine adjuvants
Nature Reviews Drug Discovery, 2021Bali Pulendran, Prabhu S Arunachalam
exaly
An overview of cytokine used as adjuvants in fish: current state and future trends
Reviews in Aquaculture, 2021Chenghua Li
exaly