Besides cholesterol lowering, statins boost antigen presentation and adaptive immune responses, suggesting new uses as adjuvants for cancer immunotherapy.
openaire +2 more sources
The effect of diatomaceous earth in live, attenuated infectious bronchitis vaccine, immune responses, and protection against challenge. [PDF]
Live virus vaccines are commonly used in poultry production, particularly in broilers. Massive application and generation of a protective local mucosal and humoral immunity with no adverse effects is the main goal for this strategy.
Corbeil, Lynette B+3 more
core +1 more source
Immunization with antigenic extracts of Leishmania associated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensis infection [PDF]
Background/Purpose: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmania antigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first ...
Cargnelutti, Diego Esteban+6 more
core +1 more source
Exocrine pancreatic cancer (pancreatic ductal adenocarcinoma) is one of the leading causes of cancer deaths in the western world, accounting for 5% of all cancer-related deaths. Only a small percentage of patients with pancreatic cancer are able to undergo potentially curative resection, even in specialized centres, and prognosis remains poor after ...
John P. Neoptolemos+2 more
openaire +3 more sources
Density and surface tension of aqueous solutions of adjuvants used for tank-mixes with pesticides
Adjuvants are surface active agents that are added to pesticide formulations or tank-mix to facilitate the mixing, application, or efficacy of these products. Addition of adjuvants changes the physico-chemical properties of spray liquid. In this work, we
J. Janků+4 more
doaj +1 more source
Accelerating vaccine development and deployment: report of a Royal Society satellite meeting. [PDF]
The Royal Society convened a meeting on the 17th and 18th November 2010 to review the current ways in which vaccines are developed and deployed, and to make recommendations as to how each of these processes might be accelerated.
Bregu, Migena+3 more
core +2 more sources
Mathematical modelling of adjuvant-enhanced active ingredient leaf uptake of pesticides [PDF]
The global importance of effective and affordable pesticides to optimise crop yield and to support health of our growing population cannot be understated. But to develop new products or refine existing ones in response to climate and environmental changes is both time-intensive and expensive which is why the agrochemical industry is increasingly ...
arxiv
Improving trial generalizability using observational studies [PDF]
Complementary features of randomized controlled trials (RCTs) and observational studies (OSs) can be used jointly to estimate the average treatment effect of a target population. We propose a calibration weighting estimator that enforces the covariate balance between the RCT and OS, therefore improving the trial-based estimator's generalizability ...
arxiv +1 more source
We thank the authors for their excellent review article. However, it is only of limited value in terms of an oncologically correct approach for specialist physicians in private practice. The authors describe in their article that after magnetic resonance tomography-aided planning, a primary R0 situation can mostly be achieved and reconstruction can be ...
Rudert, Maximilian+2 more
openaire +3 more sources
Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]
The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola+3 more
core +3 more sources