Results 51 to 60 of about 104,480 (297)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Density and surface tension of aqueous solutions of adjuvants used for tank-mixes with pesticides

Plant, Soil and Environment, 2012
Adjuvants are surface active agents that are added to pesticide formulations or tank-mix to facilitate the mixing, application, or efficacy of these products. Addition of adjuvants changes the physico-chemical properties of spray liquid. In this work, we
J. Janků, L. Bartovská, J. Soukup, M. Jursík, K. Hamouzová   +4 more
doaj   +1 more source

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

, 2016
<p><b>INTRODUCTION: </b>Pathogen recognition receptors (PRRs) recognize pathogen-associated molecular patterns, triggering the induction of inflammatory innate responses and contributing to the development of specific adaptive immune ...
K. Huygen, Marta Romano, Kris Huygen, H. Tima Giresse, M. Romano, Hermann Giresse Tima   +5 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Mucosal adjuvants and delivery systems [PDF]

, 2020
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations
Shivaramaiah, Srichaitanya, Wolfenden, Amanda, Hargis, Billy M., Pumford, Neil R., Morgan, Marion, Tellez, Guillermo L.   +5 more
core   +2 more sources

Physical–Chemical Properties, Droplet Size, and Efficacy of Dicamba Plus Glyphosate Tank Mixture Influenced by Adjuvants

Agronomy, 2021
Dicamba plus glyphosate tank mixture have been largely adopted for postemergence weed control after the development of dicamba-tolerant crops. Ammonium sulfate is commonly used as water conditioner (WC) to increase glyphosate efficacy, but its use is ...
Estefania Gomiero Polli, Guilherme Sousa Alves, Joao Victor de Oliveira, Greg Robert Kruger   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Mucosal Adjuvants And Delivery Systems [PDF]

Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations
Tellez-Isaias, Guillermo, Shivaramaiah, Srichaitanya, Wolfenden, Amanda, Hargis, Billy M., Pumford, Neil R., Morgan, Marion   +5 more
core   +4 more sources

Current status and prospects of mucosal immunity-based vaccine adjuvants and delivery systems for gastrointestinal vaccines

陆军军医大学学报
Vaccines represent the most cost-effective and efficacious approach for preventing gastrointestinal infections, and adjuvants play a pivotal role in enhancing and modulating immune responses.
LI Haibo, WANG Zhaoyi
doaj   +1 more source