Results 51 to 60 of about 136,128 (303)

Smart adjuvants

open access: yesExpert Review of Vaccines, 2007
Although vaccine adjuvants have been used for almost a century, alum is the only adjuvant licensed by the US FDA for human vaccine use. Many adjuvants studied to date have generalized inflammatory properties and lack specificity in terms of targeting immune compartments and cell populations.
Clint S, Schmidt   +2 more
openaire   +2 more sources

Effect of adjuvants on the efficiency of benthiavalicarb plus mancozeb (Valbon 1.6 kg/ha) on the control of late blight in potato [PDF]

open access: yes, 2009
Industrial adjuvants were tested in combination with benthiavalicarb plus mancozeb (Valbon 1.6 kg/ha) in the field to investigate their efficacy on foliar late blight caused by Phytophthora infestans.
De Schampheleire, Mieke   +6 more
core   +1 more source

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]

open access: yes, 2017
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio   +8 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Density and surface tension of aqueous solutions of adjuvants used for tank-mixes with pesticides

open access: yesPlant, Soil and Environment, 2012
Adjuvants are surface active agents that are added to pesticide formulations or tank-mix to facilitate the mixing, application, or efficacy of these products. Addition of adjuvants changes the physico-chemical properties of spray liquid. In this work, we
J. Janků   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Current status and prospects of mucosal immunity-based vaccine adjuvants and delivery systems for gastrointestinal vaccines

open access: yes陆军军医大学学报
Vaccines represent the most cost-effective and efficacious approach for preventing gastrointestinal infections, and adjuvants play a pivotal role in enhancing and modulating immune responses.
LI Haibo, WANG Zhaoyi
doaj   +1 more source

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

open access: yes, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR   +8 more
core   +1 more source

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