Results 51 to 60 of about 531,871 (379)

Distinctive cellular response to aluminum based adjuvants. [PDF]

, 2020
Aluminum-based adjuvants (ABAs) are used in human vaccines to enhance the magnitude of protective immune responses elicited against specific pathogens.
Bondy, Stephen C, Campbell, Arezoo, Hidalgo, Krisha, Nies, Isaac   +3 more
core  

Accelerating vaccine development and deployment: report of a Royal Society satellite meeting. [PDF]

, 2011
The Royal Society convened a meeting on the 17th and 18th November 2010 to review the current ways in which vaccines are developed and deployed, and to make recommendations as to how each of these processes might be accelerated.
Bregu, Migena, Draper, Simon J, Greenwood, Brian M, Hill, Adrian VS   +3 more
core   +2 more sources

Susceptibility of Myzus persicae, Brevicoryne brassicae and Nasonovia ribisnigri to fungal biopesticides in laboratory and field experiments [PDF]

, 2020
The aim of this study was to evaluate the potential of entomopathogenic fungi (EPF) for the control of aphid pests of field vegetable crops. Four biopesticides based on the EPF Beauveria bassiana (Botanigard ES and Naturalis L), Cordyceps fumosorosea s.l.
Chandler, Dave, Prince, Gillian
core   +1 more source

Synergistic nano-vaccine strategy for comprehensive activation of adaptive and innate immunity against Staphylococcus aureus infection

Frontiers in Immunology
For decades, Staphylococcus aureus (S. aureus) vaccine development prioritized humoral immunity, heavily relying on recombinant protein antigens adjuvanted with aluminum (Alum), particularly in multivalent formulations.
Jiayue Xi, Jiayue Xi, Minxuan Cui, Minxuan Cui, Zhuoyue Shi, Zhuoyue Shi, Zhuo Wan, Yufei Hou, Yufei Hou, Nan Sun, Nan Sun, Muqiong Li, Muqiong Li, Zhengjun Ma, Zhengjun Ma, Yupu Zhu, Yupu Zhu, Xin He, Xin He, Qian Yang, Zhuojun Shi, Huifang Nie, Huifang Nie, Chaojun Song, Li Fan, Li Fan   +25 more
doaj   +1 more source

Comparative Immunogenicity Evaluation of Characterized Chitosan-Based and Other Adjuvants for Inactivated Influenza Vaccines

Эпидемиология и вакцинопрофилактика, 2016
Chitosan-based adjuvants combine effectiveness, safety and economic feasibility and thus are quite promising for enhancement of influenza control via vaccination, however, problems of characterization and reproducibility remain unresolved; data on ...
L. M. Khantimirova, O. S. Kashirina, M. I. Chernikova, Y. M. Vasiliev   +3 more
doaj   +1 more source

Antigen-Dependent Adjuvanticity of Poly(lactic-co-glycolic acid)-polyethylene Glycol 25% Nanoparticles for Enhanced Vaccine Efficacy

Vaccines
Background: A key component in modern vaccine development is the adjuvant, which enhances and/or modulates the antigen-specific immune response. In recent years, nanoparticle (NP)-based adjuvants have attracted much research attention owing to their ...
Minxuan Cui, Jiayue Xi, Zhuoyue Shi, Yupu Zhu, Zhengjun Ma, Muqiong Li, Qian Yang, Chaojun Song, Li Fan   +8 more
doaj   +1 more source

cGAS‐STING pathway agonists are promising vaccine adjuvants

Medicinal research reviews (Print)
Adjuvants are of critical value in vaccine development as they act on enhancing immunogenicity of antigen and inducing long‐lasting immunity. However, there are only a few adjuvants that have been approved for clinical use, which highlights the need for ...
Xinyu Tian, Jiayuan Ai, Xiaohe Tian, Xiawei Wei   +3 more
semanticscholar   +1 more source

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]

, 2018
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D, Chavez, Michael, Davis, Ryan R, Ferrara, Katherine W, Fite, Brett Z, Hubbard, Neil E, Ilovitsh, Asaf, Ingham, Elizabeth S, Mahakian, Lisa M, Monjazeb, Arta M, Murphy, William J, Silvestrini, Matthew T, Tam, Sarah M, Tepper, Clifford G   +13 more
core   +1 more source

A vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challenge. [PDF]

, 2015
C3H/HeN female mice were vaccinated with native Chlamydia muridarum major outer membrane protein (MOMP), using Montanide+CpG or Alum+CpG as adjuvants. Negative control groups were immunized with ovalbumin (OVA) and the same adjuvants. As positive control,
de la Maza, Luis M, Pal, Sukumar, Tatarenkova, Olga V   +2 more
core   +1 more source

The recent advances in vaccine adjuvants

Frontiers in Immunology
Vaccine adjuvants, as key components in enhancing vaccine immunogenicity, play a vital role in modern vaccinology. This review systematically examines the historical evolution and mechanisms of vaccine adjuvants, with particular emphasis on innovative ...
Jiayin Xing, Xiangxiang Zhao, Xiaotian Li, Ren Fang, Mingrui Sun, Yang Zhang, Ningning Song   +6 more
doaj   +1 more source