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Pharmacophore Modeling for ADME

Current Topics in Medicinal Chemistry, 2013
One of the major reasons for late-stage failure of drug candidates is due to problems uncovered in pharmacokinetics during clinical trials. There is now a general consensus for earlier consideration of these effects in the drug discovery process.
Osman F, Guner, J Phillip, Bowen
openaire   +2 more sources

ADM-LDA

Journal of Information Science, 2014
Probabilistic topic models are statistical methods whose aim is to discover the latent structure in a large collection of documents. The intuition behind topic models is that, by generating documents by latent topics, the word distribution for each topic can be modelled and the prior distribution over the topic learned.
Bagheri, Ayoub   +2 more
openaire   +1 more source

ADME

2023
Predrag V. Petrovic, Paul T. Anastas
openaire   +1 more source

Validating ADME QSAR Models Using Marketed Drugs

SLAS Discovery, 2021
Pranav Shāh   +2 more
exaly  

ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential

Pharmaceuticals, 2021
Anthony Allen Reeves   +2 more
exaly  

Study of Lipophilicity and ADME Properties of 1,9-Diazaphenothiazines with Anticancer Action

International Journal of Molecular Sciences, 2023
Beata Morak-Młodawska   +2 more
exaly  

The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

Frontiers in Pharmacology, 2021
Philip Machanick   +2 more
exaly  

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