Results 191 to 200 of about 26,232 (247)

Next-Generation Artificial Intelligence for ADME Prediction in Drug Discovery: From Small Molecules to Biologics. [PDF]

Yonago Acta Med
Tanihata S, Iwata H.
europepmc   +1 more source

Safety of benfotiamine as a Novel food pursuant to Regulation (EU) 2015/2283 and the bioavailability of benfotiamine as a source of thiamin in the context of Directive 2002/46/EC on food supplements [PDF]

EFSA J
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of benfotiamine as a novel food (NF) pursuant to Regulation (EU) 2015/2283 and on the bioavailability of benfotiamine as a source of thiamin in the context of Directive 2002/46/EC ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Monika Neuhäuser‐Berthold, Miguel Prieto Maradona, Alexandros Siskos, Matthew Wright, Gabriela Precup, Silvia Valtueña Martinez, Hanna Schmierer, Karen Ildico Hirsch‐Ernst   +27 more
europepmc   +2 more sources

Mechanistic and Preliminary Safety Profiling of a Multicomponent Natural Product-Based Injectable Formulation Targeting Skin Aging-Related Pathways: A Network Pharmacology and Single-Dose Toxicity Study. [PDF]

Pharmaceuticals (Basel)
Hwang JH, Jung C.
europepmc   +1 more source

Antimicrobial, Antibiofilm, and Anticancer Activities with Molecular Docking and ADME Properties of l‑Alanine Methyl Ester and l‑Valine Methyl Ester. [PDF]

ACS Omega
Karaca TD, Sevim Akan H, Sahal G, Sert Y, Doğan A.   +4 more
europepmc   +1 more source

Role of Structural, Pharmacokinetic, and Energy Properties in the High-Throughput Prediction of Redox Potentials for Organic Molecules with Experimental Calibration. [PDF]

ACS Omega
Kalia A, Porokhin V, Blackburn B, Alba R, Ajo-Franklin C, Mevers E, Hassoun S.   +6 more
europepmc   +1 more source

Suzetrigine Is Not Expected to Have Clinically Relevant DDIs with Apixaban and Rivaroxaban Based on PBPK Modeling. [PDF]

J Clin Pharmacol
Wang G, Lakota E, Feng B, Jiang L, Liang G, Hare B.   +5 more
europepmc   +1 more source

From bench to bedside: experimental pharmacology approaches to overcome bioavailability, stability, and translational barriers of bioactive peptides from natural sources. [PDF]

Front Pharmacol
Hamadou M, Mishra SK, Abubakar AM, Başaran B, Martin Alain MM.   +4 more
europepmc   +1 more source

Design, synthesis, biological assessment, and integrated computational analysis of new pyrazole-based antimicrobial candidates. [PDF]

Sci Rep
El-Helw EAE, Hamed S, El-Ziaty AK, Alzahrani AYA, Ramadan SK.   +4 more
europepmc   +1 more source