Results 181 to 190 of about 24,681 (243)

Novel Cinnamaldehyde Hydrazones: Design, In Silico Evaluation, Synthesis, and Cytotoxic Activity. [PDF]

Molecules
Nikolova-Mladenova B, Mihaylova R, Atanasova M.   +2 more
europepmc   +1 more source

Safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) for chickens for fattening and chickens reared for laying (Huvepharma N.V.)

EFSA Journal, Volume 24, Issue 8, August 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) as a coccidiostat for chickens for fattening and chickens reared for laying.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Giovanna Martelli, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Georges Bories, Paul Brantom, Jürgen Gropp, Guido Rychen, Luca Tosti, Ruud Woutersen, Jaume Galobart, Fabiola Pizzo, Alberto Navarro‐Villa, Maria Vittoria Vettori, José Cortiñas Abrahantes, Orsolya Holczknecht   +28 more
wiley   +1 more source

Computational modeling for rational design of novel phenoxy tacrine derivatives targeting Alzheimer's disease. [PDF]

PLoS One
El Fadili M, Er-Rajy M, Mujwar S, Samadi A, Chtita S, Elhallaoui M.   +5 more
europepmc   +1 more source

COMPASS: A Computational Pipeline to Identify Linkers Predicting Ubiquitinable PROTAC‐Induced Ternary Complexes

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
COMPASS enables structure‐based screening of PROTAC linker libraries by jointly evaluating ternary complex formation and ubiquitination competence. The pipeline accurately recovers experimentally observed ternary complex geometries and identifies linkers unlikely to support productive degradation. By eliminating unproductive candidates before synthesis,
Sébastien Sueron, Sayyed Jalil Mahdizadeh, Eric Chevet, Xavier Guillory, François‐Hugues Porée, Leif A. Eriksson   +5 more
wiley   +1 more source

In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)-Triphenylphosphine Complexes with 6-Alkoxy-9-deazapurine Ligands. [PDF]

Pharmaceutics
Medvedíková M, Vančo J, Trávníček Z, Anzenbacher P.   +3 more
europepmc   +1 more source

Synthesis and biological evaluation of novel β-keto ether-triazole hybrids as dual antimicrobial and anticancer agents. [PDF]

BMC Chem
Abdel-Wahab BF, Hendy MH, Fettinger JC, Farahat AA, Mabied AF.   +4 more
europepmc   +1 more source

High-throughput phenotypic screening of Medicines for Malaria Venture's Hit Generation Library 1 identifies new nematocidal chemotypes. [PDF]

Int J Parasitol Drugs Drug Resist
Taki AC, Byrne JJ, Chang BCH, Laleu B, Wells TNC, Jabbar A, Gasser RB.   +6 more
europepmc   +1 more source

Development of an ADME gene signature for prognostic and therapeutic stratification in gastric cancer. [PDF]

Discov Oncol
Wang D, Wang X, Chen L, Wang H, Meng X, Miao Z, Zhao Y.   +6 more
europepmc   +1 more source

Structure-Activity Relationships of Hemocompatible Cationic 6-Azaindole Pyridinium Salts: Antimicrobial and Anticancer Activity. [PDF]

Molecules
Ciorteanu R, Marinas IC, Ciobanu CI, Mangalagiu II, Danac R.   +4 more
europepmc   +1 more source

Establishment and validation of a prognostic risk model based on ADME-related genes in breast cancer. [PDF]

Front Oncol
Yang Y, Yan L, Feng Y, Liu Y, Shi G, Hao J.   +5 more
europepmc   +1 more source