Results 1 to 10 of about 218,280 (292)

Pharmacokinetic study of thymol after intravenous injection and high‐dose inhalation in mouse model [PDF]

Pharmacology Research & Perspectives, 2019
Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has been
Kevin Xie, Donald P. Tashkin, Mary Z. Luo, Jack Y. Zhang   +3 more
doaj   +3 more sources

Development and evaluation of a novel nebulized dihydromyricetin formulation: enhanced pulmonary delivery and pharmacokinetic properties [PDF]

Respiratory Research
Background Respiratory diseases are a major global health burden, and inhalation therapy offers efficient pulmonary targeting and therapeutic effectiveness.
Kunyan Xu, Jianing Yang, Meng Yan, Dan Li, Wenli Du, Jing Bai, Bai Xiang   +6 more
doaj   +2 more sources

A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant Pseudomonas aeruginosa [PDF]

BMC Infectious Diseases, 2011
Background Colistin is used as last treatment option for pneumonia associated with multidrug-resistant (MDR) Pseudomonas spp.. Literature about the best administration mode (inhalation versus parenteral treatment) is lacking.
Naesens Reinout, Vlieghe Erika, Verbrugghe Walter, Jorens Philippe, Ieven Margareta   +4 more
doaj   +3 more sources

Inhalatory and intravenous colistin in treating ventilator-associated pneumonia due to acinetobacter species: Should we combine them? [PDF]

Vojnosanitetski Pregled, 2020
Background/Aim. Acinetobacter is one of the most common causes of nosocomial infections, especially ventilatorassociated pneumonia (VAP). Considering the increased presence of multidrug-resistant microorganisms and the lack of novel antibiotics, colistin
Matijašević Jovan, Gavrilović Srđan, Andrijević Ilija, Andrijević Ana, Milić Svetislava, Vukoja Marija   +5 more
doaj   +1 more source

A mixed methods analysis of cannabis use routines for chronic pain management

Journal of Cannabis Research, 2022
Background The wide heterogeneity of available cannabis products makes it difficult for physicians to appropriately guide patients. In the current study, our objective was to characterize naturalistic cannabis use routines and explore associations ...
Kevin F. Boehnke, Laura Yakas, J. Ryan Scott, Melissa DeJonckheere, Evangelos Litinas, Suzanne Sisley, Daniel J. Clauw, David A. Williams, Jenna McAfee   +8 more
doaj   +1 more source

Inhaled turmerones can be incorporated in the organs via pathways different from oral administration and can affect weight-gain of mice

Scientific Reports, 2022
Turmerones (α-turmerone, β-turmerone, and ar-turmerone) are the major volatile compounds in turmeric (Curcuma longa), a perennial herb of the ginger family.
Yuki Takemoto, Chihiro Kishi, Hinano Ehira, Nobutaka Matsui, Taichi Yamaguchi, Yuri Yoshioka, Shinichi Matsumura, Tatsuya Moriyama, Nobuhiro Zaima   +8 more
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Spirometric changes in children with asthma exposed to environmental tobacco smoke and treated with inhaled corticosteroids [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Corticosteroids are the most frequently prescribed anti-inflammatory treatment in asthma. A purpose of this study was to compare the spirometric parameters as a response to inhaled fluticasone propionate (FP) treatment in children with ...
Radić Snežana, Milenković Branislava, Gvozdenović Branislav, Međo Biljana, Dimić-Janjić Sanja   +4 more
doaj   +1 more source

Nanocrystals based pulmonary inhalation delivery system: advance and challenge

Drug Delivery, 2022
Pulmonary inhalation administration is an ideal approach to locally treat lung disease and to achieve systemic administration for other diseases. However, the complex nature of the structural characteristics of the lungs often results in the difficulty ...
Pengfei Yue, Weicheng Zhou, Guiting Huang, Fangfang Lei, Yingchong Chen, Zhilin Ma, Liru Chen, Ming Yang   +7 more
doaj   +1 more source

Aerosol Inhalation of Heat-Killed Clostridium butyricum CGMCC0313-1 Alleviates Allergic Airway Inflammation in Mice

Journal of Immunology Research, 2022
Epidemiological studies have shown that exposure to beneficial microorganisms can reduce the risk of asthma, but the clinical use of live probiotics is controversial due to the risk of infection.
Laodong Li, Qixiang Sun, Huan Xiao, Qiannan Zhang, Siyue Xu, Lejin Lai, Zhengning Li, Chaoqian Li   +7 more
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Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing

Frontiers in Pharmacology, 2022
To avoid adverse drug reactions associated with injection, off-label nebulization of Tanreqing (TRQ) injection is often used in China to treat respiratory diseases.
Teng-Fei Chen, Ling Song, Yun-Hang Gao, Han Li, Jian-Liang Li, Hong-Ping Hou, Bo Peng, Hui-Ying Wang, Wen-Hao Cheng, Zu-Guang Ye, Ying-Fei Li, Guang-Ping Zhang   +11 more
doaj   +1 more source