Nanoparticle-Mediated Nose-to-Brain Delivery for Ischemic Stroke Therapy: Preclinical Insights. [PDF]
Park J, Riew TR.
europepmc +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Comparison of Oral and Intranasal Midazolam Premedication in Children Undergoing Cleft Lip and Palate Surgery: A Randomized Controlled Trial. [PDF]
Hashimoto M +6 more
europepmc +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Advances in the Clinical Application of MAC: A Review of Drug Selection, Combination Therapy, and Administration Methods. [PDF]
Lei XH, Yang WW, Luo X, Rao PG, Guo R.
europepmc +1 more source
Intranasal delivery of Odorranalectin-modified lipid nanoparticles for multi-targeted therapy of Alzheimer's disease. [PDF]
Zhang Y +7 more
europepmc +1 more source
Strategies to deliver peptide drugs to the brain [PDF]
Lalatsa, Katerina +2 more
core +1 more source
Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna +10 more
wiley +1 more source
Epinephrine nasal spray for the treatment of anaphylaxis: perspectives in pediatrics. [PDF]
Crescioli G +6 more
europepmc +1 more source

