Clinical efficacy of intravaginal recombinant lysostaphin administration on endometritis in sows [PDF]
Recombinant lysostaphin has been used for the treatment of cow endometritis and mastitis in China. To our knowledge, no scientific effort has been made to evaluate the efficacy of lysostaphin in sows with clinical endometritis.
Guizi Ye+8 more
doaj +4 more sources
Intravaginal administration of estradiol benzoate capsule for estrus synchronization in goats
Estrus synchronization requires multiple treatments of hormonal drugs, requiring considerable time and cost. The aim of the present study was to develop an estrus synchronization protocol using intravaginal administration of estradiol benzoate (EB ...
Sayaka MATSUMOTO+2 more
doaj +5 more sources
First-in-human study to assess the pharmacokinetics, tolerability, and safety of single-dose oxybutynin hydrochloride administered via a microprocessor-controlled intravaginal ring [PDF]
Polymeric drug-releasing vaginal rings are useful for both local and systemic administration of drugs via the intravaginal route. Typically, they provide continuous sustained or controlled release of drug(s) over extended time periods, thereby avoiding ...
Willem de Laat+8 more
doaj +2 more sources
The objective of the present study was to develop and evaluate a sustained release vaginal progesterone (P4) capsule containing a mixture of mucoadhesive polymer and silicone fluid.
Natsumi ENDO+4 more
doaj +4 more sources
Intravaginal probiotics before embryo transfer do not improve pregnancy rates in recurrent implantation failure cases: An RCT [PDF]
Background: Considering the considerable influence of the vaginal microbiome on endometrial receptivity and embryo implantation, we hypothesized that cases of recurrent implantation failure (RIF) might benefit from the intravaginal probiotic ...
Mina Naghi Jafarabadi+4 more
doaj +2 more sources
Myo-inositol in the treatment of male factor infertility [PDF]
About 187 million couples worldwide suffer from infertility, with the male factor being diagnosed in 2070% of cases. The main cause of idiopathic infertility has been recognized as the adverse effects of reactive oxygen species.
Evgenia V. Shikh+3 more
doaj +1 more source
Comparison of Two Different Intervals of Misoprostol Administration in Second Trimester Abortions
Objective: Comparison of two different intervals of misoprostol administration after mifepristone in second trimester abortions. Materials and methods: This 12-month prospective study was conducted at a tertiary care facility.
Anjali Gupta+6 more
doaj +1 more source
Evaluation of TLR agonists as potential mucosal adjuvants for HIV gp140 and tetanus toxoid in mice. [PDF]
In the present study we investigate the impact of a range of TLR ligands and chitosan as potential adjuvants for different routes of mucosal immunisation (sublingual (SL), intranasal (IN), intravaginal (IVag) and a parenteral route (subcutaneous (SC)) in
Viviana Buffa+3 more
doaj +1 more source
Background and Objectives: Preterm birth (PTB) is associated with important neonatal mortality and morbidity. The aim of this study was to retrospectively evaluate the average treatment effects on the treated and the efficacity of various therapeutic ...
Alina-Madalina Luca+12 more
doaj +1 more source
The climacteric is considered a natural phase in a woman’s aging process and is defined as the period starting from the decline in ovarian activity until after the end of ovarian function. Genitourinary syndrome of menopause (GSM) is commonly observed in
Valentina Lucia La Rosa+8 more
doaj +1 more source