Results 21 to 30 of about 9,279 (208)

Quantifying Policy Administration Cost in an Active Learning Framework [PDF]

open access: yesarXiv, 2023
This paper proposes a computational model for policy administration. As an organization evolves, new users and resources are gradually placed under the mediation of the access control model. Each time such new entities are added, the policy administrator must deliberate on how the access control policy shall be revised to reflect the new reality.
arxiv  

Intravaginal rings for continuous low-dose administration of cervical ripening agents [PDF]

open access: yesInternational Journal of Pharmaceutics, 2018
Intravaginal rings (VRs) have been widely reported for administration of pharmaceutical drugs - most notably estrogens, progestogens and antiretrovirals - to the vagina for clinical benefit. Here, for the first time, we describe the design, manufacture and preclinical testing of VRs for sustained/controlled release of the cervical ripening agents ...
Wang, Yujing   +3 more
openaire   +4 more sources

Intra-vaginal gemcitabine-hybrid nanoparticles for effective cervical cancer treatment

open access: yesOpenNano, 2022
Aim: This study aims to develop and evaluate hybrid nanoparticles for the effective intravaginal delivery of the anticancer gemcitabine in cervical cancer rat model.
Mona Elhabak   +2 more
doaj  

Enhanced Delivery of Imatinib into Vaginal Mucosa via a New Positively Charged Nanocrystal-Loaded in Situ Hydrogel Formulation for Treatment of Cervical Cancer

open access: yesPharmaceutics, 2019
The present study was carried out to investigate the potential of cationic functionalization on imatinib nanocrystals to improve the mucoadhesiveness and, thus, delivery to the lesion of cervicovaginal tumors.
Li-qian Ci   +10 more
doaj   +1 more source

Influence of administration of Staphylococcus aureus cells suspension on composition of vaginal microflora of mice under immunosupression

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
The influence of intravaginal administration of cells of indigenous strain of Staphylococcus aureus on composition of vaginal microbiocenosis was studied.
O. S. Voronkova   +3 more
doaj   +1 more source

Research of acute toxicity of the drug HEXIA

open access: yesФармацевтичний журнал, 2018
Diseases of the genitourinary system caused by pathogenic and potentially pathogenic microorganisms, which result into disbiosis of urinary organs, remain an urgent problem of dermatovenereology, gynecology and urology, despite the fact that there is a ...
V. L. Karbovskyy   +3 more
doaj   +1 more source

Heterologous prime-boost vaccination based on Polymorphic protein D protects against intravaginal Chlamydia trachomatis infection in mice

open access: yesScientific Reports, 2022
The control of the worldwide spread of sexually transmitted Chlamydia trachomatis (Ct) infection urgently demands the development of a preventive vaccine.
Romina Cecilia Russi   +6 more
doaj   +1 more source

The role of topic vaginal products in posthysterectomy vaginal atrophy [PDF]

open access: yesRomanian Medical Journal, 2021
Vaginal atrophy represents a frequently encountered condition which is significantly correlated with decreased amounts of circulating estrogen levels. It is usually characterized by the presence of burning, itching, irritation and dyspareunia.
Nicolae Bacalbasa   +6 more
doaj   +1 more source

Abortion caused by intravaginal self-administration of Misoprostol: a case report

open access: yesRomanian Journal of Legal Medicine, 2019
The authors present a case of a 38 years old woman, 21 weeks pregnant, that went to the emergency department, where she gave birth to a stillborn male fetus. A gynaecological examination revealed three partially dissolved tablets in the vagina. Chemical laboratory tests on the tablets showed they were Misoprostol (MP) tablets.
Martina Focardi   +5 more
openaire   +1 more source

Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer

open access: yesNanomaterials, 2021
To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang   +6 more
doaj   +1 more source

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