Results 21 to 30 of about 13,775 (209)

Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA [PDF]

, 2016
peer reviewedTopical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a ...
Furst, Tania, Dakwar, George, Zagato, Elisa, Lechanteur, Anna, Remaut, Katrien, Evrard, Brigitte, Braeckmans, Kevin, Piel, Geraldine   +7 more
core   +1 more source

Reproductive Performance of Female Rabbits Inseminated with Extenders Supplemented with GnRH Analogue Entrapped in Chitosan-Based Nanoparticles

Animals, 2023
Rabbit is a reflexively ovulating species. Accordingly, in the practice of artificial insemination (AI) ovulation must be induced via exogenous GnRH (Gonadotropin-Releasing Hormone) administration, which may be performed intramuscularly, subcutaneously ...
Maria Pilar Viudes-de-Castro, Francisco Marco Jimenez, José Salvador Vicente   +2 more
doaj   +1 more source

Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]

, 2018
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard, Abramov, Agerberth, Aldunate, Alexander, Allsworth, Anahtar, Ando, Appelmelk, Aroutcheva, Ashida, Baker, Baranger, Beigi, Berlutti, Berlutti, Berlutti, Bradshaw, Bradshaw, Britigan, Brooks, Brotman, Bullen, Byrne, Caccavo, Cauci, Cherpes, Cole, Cole, Conti, Corbin, Corbishley, Cutone, Cutone, De Gregorio, Deese, Delgado-Rizo, Drannik, Elass, Ericksen, Eschenbach, Eslami, Frioni, Fritsch, Gajer, He, He, Hearps, Hedges, Hein, Hemalatha, Hickey, Hiemstra, Hill, Hill, Hudić, Hummelen, Jakobsson, Judd, Kaushic, Kelver, Klebanoff, Kohlhoff, Kościuczuk, Lamont, Larsen, Legrand, Legrand, Leitch, Maggi, Marrazzo, Martin, Martin, Mastromarino, Mastromarino, Mastromarino, Meijerink, Michieli, Moberg, Morrison, Morrison, Nardis, Ness, Niyonsaba, Olmsted, Olmsted, Omata, Ong, O’Hanlon, Paesano, Paesano, Paesano, Paesano, Paesano, Pazgier, Peipert, Peipert, Petrova, Pino, Puddu, Quayle, Rampersauda, Raulston, Ravel, Ravel, Redondo-Lopez, Reghunathan, Rizzo, Rizzo, Roberton, Rosa, Rönnqvist, Santiago, Santiago, Sarkar, Sessa, Shakibaei, Shust, Singh, Singh, Spadaro, Spear, Spurbeck, Srinivasan, Srinivasan, Stallmann, Straub, Stríz, Suzuki, Tachedjian, Teng, Teng, Teng, Tuyama, Valenti, Valenti, Valenti, Valore, Van de Wijgert, Vargas-Villavicencio, Vielfort, Vitali, Walther-António, Ward, Weinberg, Wiesenfeld, Wiesner, Wilson, Wilson, Wilson, Wira, Wira, Wira, Wira, Wu, Yamamoto, Zhou   +156 more
core   +2 more sources

Intravaginal lactic Acid bacteria modulated local and systemic immune responses and lowered the incidence of uterine infections in periparturient dairy cows. [PDF]

PLoS ONE, 2014
The objective of this investigation was to evaluate whether intravaginal infusion of a lactic acid bacteria (LAB) cocktail around parturition could influence the immune response, incidence rate of uterine infections, and the overall health status of ...
Qilan Deng, John F Odhiambo, Umar Farooq, Tran Lam, Suzanna M Dunn, Burim N Ametaj   +5 more
doaj   +1 more source

Continuous acceleration of neural activity of the GnRH pulse generator during chronic peripheral infusion of neurokinin 3 receptor agonist in goats

The Journal of Reproduction and Development, 2023
Secretion of pulsatile gonadotropin-releasing hormone (GnRH) is essential for reproduction. Kisspeptin neurons in the arcuate nucleus (ARC), which coexpress neurokinin B (NKB) and its receptor (NK3R), are believed to be components of the GnRH pulse ...
Takashi YAMAMURA, Hiroaki OKAMURA, Yoshihiro WAKABAYASHI   +2 more
doaj   +1 more source

Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections

Antibiotics, 2021
Patients with chronic urinary and urogenital multidrug resistant bacterial infections received phage therapy (PT) using intravesical or intravesical and intravaginal phage administration.
Sławomir Letkiewicz, Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Maciej Żaczek, Beata Weber-Dąbrowska, Andrzej Górski   +5 more
doaj   +1 more source

Portal Venous Thrombosis Associated with Use of Etonogestrel/ethinyl Estradiol Vaginal Ring [PDF]

, 2020
Introduction: Portal venous thrombosis is a life-threatening cause of abdominal pain. In younger patients, heritable thrombophilias, pregnancy, tobacco use, and oral contraceptives are associated.Case Report: A 26-year-old woman prescribed contraceptive ...
Bailey, Katelynn E., Tranovich, Michael J.   +1 more
core  

Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]

, 2017
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +5 more
core   +1 more source

Intravaginal rings for continuous low-dose administration of cervical ripening agents [PDF]

International Journal of Pharmaceutics, 2018
Intravaginal rings (VRs) have been widely reported for administration of pharmaceutical drugs - most notably estrogens, progestogens and antiretrovirals - to the vagina for clinical benefit. Here, for the first time, we describe the design, manufacture and preclinical testing of VRs for sustained/controlled release of the cervical ripening agents ...
Wang, Yujing, Boyd, Peter, Hunter, Alyson, Malcolm, R. Karl   +3 more
openaire   +4 more sources

Development and Evaluation of a Thermosensitive In Situ Gel Formulation for Intravaginal Delivery of Lactobacillus gasseri

Pharmaceutics, 2022
In situ administration of vaginal probiotics has been proposed as an effective prevention strategy against gynecological diseases caused by microecological disorders.
Ye Zhao, Tianyuan Wang, Ziyi Chen, Hao Ren, Ping Song, Yingying Zhu, Shan Liang, Chimeng Tzeng   +7 more
doaj   +1 more source