Results 121 to 130 of about 34,804 (275)
Beyond the Epidural: Reframing Analgesia for the Modern Oesophagectomy
ANZ Journal of Surgery, EarlyView.A novel analgesic framework for minimally invasive oesophagectomy to facilitate functional recovery.
William Thomas Birkett +6 more
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
VaccinesSublingual vaccines offer the benefits of inducing mucosal immunity to protect against respiratory viruses, including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and influenza, while also enabling needle-free self-administration.
Tetsuro Yamamoto +6 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Sublingual Administration of Tacrolimus in Liver Transplant Patient with Intestinal Malabsorption
Indian Journal of TransplantationImmunosuppressive therapy after liver transplantation typically combines a calcineurin inhibitor, an antimetabolite, and corticosteroids. Tacrolimus, due to its narrow therapeutic margin and variability in blood levels, requires therapeutic drug ...
Aritz Merchán Flores +3 more
doaj +1 more source
Clinical &Experimental Allergy, EarlyView.Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić +10 more
wiley +1 more source
Clinical &Experimental Allergy, EarlyView.3 years follow‐up study to a DBPC dose‐finding trial investigating subcutaneous immunotherapy with T502 in birch‐pollen induced allergic rhinoconjunctivitis. 154 birch‐pollen allergic adults received short‐course treatment of 10,000 mTU/mL of T502 for 2 years and were observed during the next season without treatment.
Ralph Mösges +15 more
wiley +1 more source
A cross-comparative pharmacokinetic study of Klimalanin (ingestion or sublingual intake)
Гинекология, 2013 Beta-alanine (Klimalanin) is generally used for the treatment and prevention of vasomotor disturbances (hot flushes) in menopausal period. This paper presents the results of a comparative analysis of the beta-alanine pharmacokinetics with a single ...
I S Yurghel +7 more
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