Results 81 to 90 of about 2,148,141 (263)

Critical constraints to ecological buffering in a rapidly changing Arctic: A long‐term seabird study

Journal of Animal Ecology, EarlyView.
Drawing on two decades of research in East Greenland, this study shows that little auks, key seabird indicators of Arctic ecosystem health, can adapt to rapid environmental change through behavioural flexibility. However, increasing storms and mercury pollution are pushing resilience to its limits, providing an early warning of broader Arctic ...
David Grémillet, Françoise Amélineau, Ann M. A. Harding, Jérôme Fort   +3 more
wiley   +1 more source

Development of a sublingual allergy vaccine for grass pollinosis

, 2010
Franco Frati1,2, Silvia Scurati1, Paola Puccinelli1, Marie David3, Cecile Hilaire4, Maurizio Capecce4, Francesco Marcucci2, Cristoforo Incorvaia51Medical and Scientific Department, Stallergenes, Milan, Italy; 2University Department of Medical and ...
Silvia Scurati, Franco Frati, et al, Paola Puccinelli   +3 more
core  

Preoperative Versus Postoperative Sublingual Misoprostol in Reducing Blood Loss during and after Primary Elective Cesarean Section [PDF]

Zagazig University Medical Journal
Background: One of the major risks associated with cesarean sections (CS) is blood loss. According to earlier studies, misoprostol effectively lowers intraoperative blood loss during caesarian sections and in the primary postpartum period regardless of ...
Ali Ali, Sherin El-Shazly, Yahya Mahdy Nada   +2 more
doaj   +1 more source

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

Allergy, EarlyView.
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal, Davide P. Caimmi, Pablo Rodriguez del Rio, Óscar Lado‐Baleato, Francisco Gude, Pilar Rico‐Nieto, Thomas B. Casale, Jorge A. Aguilar, Maryam Ali Al‐Nesf, Fatima Ashkanani, Adeeb Bulkhi, Juan C. Cardet, Claudia Almendarez, Silvia Caimmi, Iván Cherrez, Enza D’Auria, Stephanie Dramburg, Motohiro Ebisawa, Naoko Fusayasu, Maximiliano Gomez, Sandra Gonzalez‐Diaz, Carla Irani, Andrey Kamaev, Connie Katelaris, Narinder Kaur, Oksana KurBacheva, José I. Larco, Désirée Larenas‐Linnemann, Margaret Li, Olga Patricia Monge‐Ortega, Pablo Moreno, Oliver Pfaar, Cesar F. Pozo‐Beltrán, Marta E. Rubio, Jorge Sanchez, Giovanni Sedo, Silvia Uriarte, Lin Yang, Hao Chen, Rongfei Zhu, Pascal Demoly, Moises A. Calderon, on behalf of the CHOICE‐Global Survey Team   +42 more
wiley   +1 more source

Absorption of Vitamin B12 in Older Adults: Advances and Challenges in Sublingual Administration

Drugs and Drug Candidates
The aim of this review is to analyze current routes for the administration and absorption of vitamin B12 in older adults, with a special focus on the sublingual route using orodispersible films, and evaluate the advances, materials, and challenges ...
Antonella Quijada, Benjamín Claria, Paula Jiménez, Paula García, Álvaro Pérez, María Elsa Pando   +5 more
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Investigating the Analgesic Effect of Sublingual Glycerol Trinitrate (GTN) Spray as an Alternative Treatment in Renal Colic Pain: A Triple-Blinded Randomized Controlled Trial

Acta Medica Iranica
Renal colic, a severe pain caused by renal and urethral calculi, causes millions of patients to visit the emergency department (ED) worldwide each year.
Paria Sadat Ramezany, Mohammed Ali Shadram, Ahmad Reza Dehpour, Razieh Mohammad Jafari, Morteza Saeedi, Mehrad Aghili, Javad Seyedhosseini   +6 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Comparison of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: To evaluate the effects of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion. Materials and methods: From January 2006 to December 2011, 173 women received an 800-μg vaginal loading dose ...
Ming-Chao Huang, Ching-Hung Hsieh, Jian-Pei Huang, Hsiu-Ting Tsai, Maw-Sheng Lee   +4 more
doaj   +1 more source