Results 41 to 50 of about 2,390,183 (202)

Topical Nifedipine Administration for Secondary Prevention in Frostbitten Patients [PDF]

Frontiers in Physiology, 2020
Frostbite is a cold-related injury with a growing incidence among healthy subjects. Sequelae after frostbite are frequent and vary among individuals. Here, we studied the thermal response in the digits of hands and feet of five subjects who had recovered from previous frostbite, except for their lasting sequelae.
Carceller, Anna, González Torcal, Juan Pedro, Viscor Carrasco, Ginés   +2 more
openaire   +5 more sources

The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders, 2018
BackgroundThe combined administration of intravenous (IV) and topical tranexamic acid (TXA) in primary total knee (TKA) knee remains controversial. The purpose of this meta-analysis was to assess the efficacy and safety of combined administration of IV ...
Huazhang Xiong, Yi Liu, Yi Zeng, Yuangang Wu, B. Shen   +4 more
semanticscholar   +1 more source

Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases

Pharmaceutics, 2018
Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable).
Rinda Devi Bachu, Pallabitha Chowdhury, Zahraa H. F. Al-Saedi, Pradeep K. Karla, Sai H. S. Boddu   +4 more
doaj   +1 more source

Central Serous Chorioretinopathy in a 14-year-old atopic boy: a case report

Italian Journal of Pediatrics, 2023
Background Corticosteroids are widely used in medicine. Few cases of central serous chorioretinopathy (CSC) have been reported following topical corticosteroid administration.
Stefano Ranno, Liviana Fontanel, Edoardo Ruggiero, Paolo Nucci, Paolo Radice, Simone Donati   +5 more
doaj   +1 more source

Tranexamic acid in melasma: A focused review on drug administration routes

Journal of Cosmetic Dermatology, 2023
Melasma is a disorder of hyperpigmentation and vascularization often found in women between the ages of 20 and 40. The pathogenesis is unknown, but melasma often occurs in sun‐exposed areas of the face, forearms, and back.
Hailey Konisky, Eliza Balazic, J. Jaller, Urmi Khanna, K. Kobets   +4 more
semanticscholar   +1 more source

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

Pharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang, Hongmei Hu, Qian Jing, Zhi Wang, Zehui He, Tong Wu, Nian-Ping Feng   +6 more
doaj   +1 more source

Topical versus intravenous administration of tranexamic acid in primary total hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials

Orthopedic Reviews, 2016
Tranexamic acid (TA) is widely used by orthopedic surgeons to decrease blood loss and the need for transfusion following total hip arthroplasty (THA). Although both intravenous and topical applications are described in the literature, there remains no ...
Sammy A. Hanna, Anoop Prasad, Joshua Lee, Pramod Achan   +3 more
doaj   +1 more source

The efficacy and safety of topical administration of tranexamic acid in spine surgery: a meta-analysis

Journal of Orthopaedic Surgery and Research, 2018
BackgroundWe conducted a meta-analysis from randomized controlled trials (RCTs) and non-RCTs to assess the efficacy and safety of tranexamic acid (TXA) in spine surgery.MethodsPotentially relevant academic articles were identified from the Cochrane ...
W. Luo, Ru-xin Sun, H. Jiang, Xin-long Ma   +3 more
semanticscholar   +1 more source

Comparative pharmacokinetics of fluralaner in dogs and cats following single topical or intravenous administration

Parasites & Vectors, 2016
BackgroundBravecto™ Chewable Tablets for Dogs, containing fluralaner as active ingredient, is an innovative treatment for flea and tick infestations that provides safe, rapid and long acting efficacy after a single oral administration in dogs.
S. Kilp, Diana Ramirez, M. Allan, Rainer K. A. Roepke   +3 more
semanticscholar   +1 more source

Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats

Current Research in Parasitology and Vector-Borne Diseases, 2023
Felpreva® for cats contains the new acaricidal/insecticidal active ingredient tigolaner in a fixed combination with the nematocidal and cestocidal compounds emodepside and praziquantel, respectively.
Norbert Mencke, Wolfgang Bäumer, Kristine Fraatz, Ralph Krebber, Marc Schneider, Katrin Blazejak   +5 more
doaj