Serum Concentrations and Pharmacokinetics of Tranexamic Acid after Two Means of Topical Administration in Massive Weight Loss Skin-Reducing Surgery [PDF]
Background: Topical administration of tranexamic acid to reduce bleeding is receiving increasing attention, as it is inexpensive, simple, and possibly beneficial in most surgery.
Ausen, Kjersti+6 more
core +1 more source
Bisphosphonate: Brief Review of Its Development for Usage in Dentistry
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Tita Ratya Utari
doaj +1 more source
Use of ozone-based eye drops. A series of cases in veterinary and human spontaneous ocular pathologies [PDF]
Conjunctivitis, keratoconjunctivitis, and corneal ulcers are common eye disorders frequently diagnosed in both humans and animals, and are currently treated by topical administration of eye drops containing anti-inflammatory and antibacterial agents. The
Marchegiani, Andrea+3 more
core +3 more sources
Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Hamid Reza Ghafarian Shirazi+3 more
doaj +2 more sources
Breaking down the Barrier: Topical Liposomes as Nanocarriers for Drug Delivery into the Posterior Segment of the Eyeball [PDF]
Topical instillation is the most widely preferred noninvasive route of drug administration to treat diseases affecting the anterior segment of the eye. Nonetheless, the ocular bioavailability for deeper ocular tissues is very low.
Altamirano-Vallejo, Juan C.+4 more
core +1 more source
Essential Oils and Isolated Terpenes in Nanosystems Designed for Topical Administration: A Review
Essential oils are natural products with a complex composition. Terpenes are the most common class of chemical compounds present in essential oils. Terpenes and the essential oils containing them are widely used and investigated by their pharmacological ...
S. P. de Matos+4 more
semanticscholar +1 more source
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha+3 more
doaj +1 more source
Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher+4 more
core +1 more source
Transdermal and Topical Drug Administration in the Treatment of Pain
The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients’ age, comorbidities, and appropriate choice of analgesic, its dose and ...
W. Leppert+3 more
semanticscholar +1 more source
Objective This study aimed to compare the effects of intravenous, topical and combined routes of tranexamic acid (TXA) administration on blood loss and transfusion requirements in patients undergoing total knee arthroplasty (TKA) and total hip ...
Qi Sun+5 more
semanticscholar +1 more source