Results 121 to 130 of about 326,995 (379)

Immunotherapy in Cervical and Endometrial Cancer: Current Landscape and Future Directions

Life
Gynecological cancers pose a significant burden on women’s health worldwide, necessitating innovative treatment approaches. Immunotherapy has emerged as a promising strategy, harnessing the body’s immune system to combat cancer.
Dimitrios Stefanoudakis, Evaggelia Karopoulou, Alkis Matsas, Georgia Anna Katsampoula, Ermioni Tsarna, Eleni Stamoula, Panagiotis Christopoulos   +6 more
doaj   +1 more source

Immune-mediated mechanisms influencing the efficacy of anticancer therapies [PDF]

, 2015
Conventional anticancer therapies, such as chemotherapy, radiotherapy, and targeted therapy, are designed to kill cancer cells. However, the efficacy of anticancer therapies is not only determined by their direct effects on cancer cells but also by off ...
Acharyya, Affara, Ahn, Ahn, Albanesi, Alizadeh, Anders, Andreu, Apetoh, Azab, Balachandran, Bald, Begg, Borg, Bos, Broz, Bruchard, Burnette, Casares, Cavnar, Chabner, Chao, Chung, Ciampricotti, Clynes, Coffelt, Cooper, Dankort, De Palma, De Palma, De Palma, De Palma, De Palma, de Visser, de Visser, Demaria, DeNardo, DeNardo, Deng, Deng, Derksen, Devaud, DeVita, Di Maio, Di Mitri, Diaz-Montero, Dijkgraaf, Dirkx, Dranoff, Du, DuPage, DuPage, Engelhardt, Ferrari de Andrade, Finke, Fischer, Francia, Fridlender, Gabrilovich, Gabrusiewicz, Ganesan, Garbe, Germano, Ghiringhelli, Ghiringhelli, Goodman, Grugan, Guerin, Guerriero, Gupta, Guy, Guy, Hagerling, Hamid, Han, Hanahan, Hanahan, Hanna, Hannesdottir, Herbst, Highfill, Ho, Hodi, Houthuijzen, Huang, Imai, Jiang, Kanterman, Karin E. de Visser, Kioi, Kitamura, Klug, Knight, Ko, Kodumudi, Kowanetz, Koya, Kozin, Krumbhaar, Landsberg, Le, Ledford, Lee, Lesterhuis, Li, Liauw, Lin, Lin, Liu, Lutsiak, Ma, Ma, Manning, Mantovani, Maroulakou, Matsumura, Mattarollo, Mazzieri, Minard-Colin, Mitchem, Mokyr, Muller, Muller, Munoz, Murdoch, Nakasone, Nefedova, Noh, North, Noy, Ojalvo, Olive, Pahler, Pander, Pardoll, Park, Paulus, Pienta, Pollizzi, Porembka, Powell, Powles, Priceman, Pucci, Pyonteck, Qian, Quail, Rakhra, Ramakrishnan, Reits, Ries, Robert, Robert, Robert, Rolny, Ruffell, Sahu, Sandhu, Savage, Schioppa, Seth B. Coffelt, Sevko, Shevchenko, Shojaei, Shojaei, Shojaei, Shree, Shrimali, Simpson, Singh, Singh, Singh, Sistigu, Smith, Snyder, Sommer, Srivastava, Stanley, Stockmann, Straussman, Suzuki, Suzuki, Swierczak, Takeshima, Talmadge, Taskinen, Terme, Toso, Tumeh, Ugel, Vanneman, Verbrugge, Vincent, Walter, Wang, Wang, Welford, Wilmott, Wu, Wu, Xu, Xue, Yang, Youn, Zhang, Zhang, Zhu   +206 more
core   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Gamma-delta (γδ) T cells: friend or foe in cancer development?

Journal of Translational Medicine, 2018
Background γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains with diverse structural and functional heterogeneity.
Yijing Zhao, Chao Niu, Jiuwei Cui
doaj   +1 more source

Adoptive Cell Transfer: Is it a Promising Immunotherapy for Colorectal Cancer?

Theranostics, 2018
The last decade has witnessed significant advances in the adoptive cell transfer (ACT) technique, which has been appreciated as one of the most promising treatments for patients with cancer.
Jia-qiao Fan, D. Shang, B. Han, Jianxun Song, Hailong Chen, Jin-Ming Yang   +5 more
semanticscholar   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]

, 2013
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E., Denniss, Frances, Guinn, Barbara-Ann, Khan, Ghazala, Sigurdardottir, Dagmar   +4 more
core   +2 more sources

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Metabolic aspects of adoptive immunotherapy of tumors

Успехи молекулярной онкологии, 2017
In wide number of approaches to treatment of cancer immunotherapy plays special role. This approach exploits capabilities of immune system to support genetic constancy of different cells and tissues of the organism.
D. B. Kazanskiy, Yu. Yu. Silaeva, A. A. Kalinina, M. A. Zamkova, L. M. Khromykh, N. A. Persiyantseva, L. Kh. Dzholokhava   +6 more
doaj   +1 more source

Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. [PDF]

, 2019
Tumor cells harboring stem-like/cancer stem cell (CSC) properties have been identified and isolated from numerous hematological and solid malignancies.
Ames, Erik, Bouzid, Lyes A, Canter, Robert J, Darrow, Morgan A, Grossenbacher, Steven K, Judge, Sean J, Luna, Jesus I, Murphy, William J, Sturgill, Ian R   +8 more
core   +1 more source