Results 231 to 240 of about 306,104 (338)

4-1BB Is Superior to CD28 Costimulation for Generating CD8+ Cytotoxic Lymphocytes for Adoptive Immunotherapy [PDF]

, 2007
Hua Zhang, Kristen Snyder, Megan M. Suhoski, Marcela V. Maus, Veena Kapoor, Carl H. June, Crystal L. Mackall   +6 more
openalex   +1 more source

Long-term adoptive immunotherapy achieves complete response and bone lesion repair in an elderly patient with macrofocal multiple myeloma. [PDF]

Cancer Pathog Ther
Song Y, Lu X, Wang J, Cai L, Liu T, Wu L, Sun L, Xu X, Gao C, Yang B.   +9 more
europepmc   +1 more source

Donor selection for adoptive immunotherapy with NK cells in AML patients: Comparison between analysis of lytic NK cell clones and phenotypical identification of alloreactive NK cell repertoire. [PDF]

Front Immunol, 2023
Meazza R, Ruggeri L, Guolo F, Minetto P, Canevali P, Loiacono F, Ciardelli S, Bo A, Luchetti S, Serio A, Zannoni L, Retière C, Colomar-Carando N, Parisi S, Curti A, Lemoli RM, Pende D.   +16 more
europepmc   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Adoptive immunotherapy against kidney targets in dog-leukocyte antigen-identical mixed hematopoietic canine chimeras

, 2003
Christian Junghanß, Alessandra Takatu, Marie-Térèse Little, Jan Maciej Zaucha, Eustacia Zellmer, Murad Y. Yunusov, George Sale, George E. Georges, Rainer Storb   +8 more
openalex   +1 more source

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy [PDF]

, 2008
Christian S. Hinrichs, Rosanne Spolski, Chrystal M. Paulos, Luca Gattinoni, Keith Kerstann, Douglas C. Palmer, Christopher A. Klebanoff, Steven A. Rosenberg, Warren J. Leonard, Nicholas P. Restifo   +9 more
openalex   +1 more source

Preclinical evaluation and first-in-dog clinical trials of PBMC-expanded natural killer cells for adoptive immunotherapy in dogs with cancer. [PDF]

J Immunother Cancer
Razmara AM, Farley LE, Harris RM, Judge SJ, Lammers M, Iranpur KR, Johnson EG, Dunai C, Murphy WJ, Brown CT, Rebhun RB, Kent MS, Canter RJ.   +12 more
europepmc   +1 more source

An outlook on antigen-specific adoptive immunotherapy for viral infections with a focus on COVID-19. [PDF]

Cell Immunol, 2021
Monzavi SM, Naderi M, Ahmadbeigi N, Kajbafzadeh AM, Muhammadnejad S.   +4 more
europepmc   +1 more source

AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering

Advanced Science, EarlyView.
AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun, Jiayi Yuan, Divya Jaiswal, Jingxuan Ge, Tianjian Liang, Jiahui Wei, Jinghong Cao, Yulong Li, Xiaojie Chu, Yan Chen, Ying Xue, Wei Li, Tingjun Hou, Zhiwei Feng   +13 more
wiley   +1 more source

172Ex vivo engineering of previously thawed and cryopreserved umbilical cord blood (UCB) with interleukin (IL)-2, IL-7, IL-12 and anti-CD3 for expansion of cytotoxic T lymphocytes (CTL): Promising strategy for adoptive cellular immunotherapy (ACI) post UCB transplantation (T)

, 2003
Mitchell S. Cairo, Janet Ayello, C. van de Ven   +2 more
openalex   +1 more source