Results 241 to 250 of about 326,995 (379)

Empowering Biomedical Research with Foundation Models in Computational Microscopy: A Systematic Review

Advanced Intelligent Systems, EarlyView.
The integration of foundation models into computational microscopy revolutionizes biomedical research by enhancing imaging resolution, accelerating data analysis, and enabling real‐time biological interpretation. This systematic review critically examines recent advancements, highlights translational challenges, and discusses the transformative ...
Di Ding, Tianliang Yao, Genyi Feng, Xueqing Gao, Xusen Sun, Rong Luo   +5 more
wiley   +1 more source

Compassionate access to virus-specific T cells for adoptive immunotherapy over 15 years. [PDF]

Nat Commun
Neller MA, Ambalathingal GR, Hamad N, Sasadeusz J, Pearson R, Holmes-Liew CL, Singhal D, Tunbridge M, Ng WY, Sharplin K, Moore A, Deambrosis D, Soosay-Raj T, McNaughton P, Whyte M, Fraser C, Grigg A, Kliman D, Bajel A, Cummins K, Dowling M, Yeoh ZH, Harrison SJ, Khot A, Tan S, Roos I, Koo RM, Dohrmann S, Ritchie D, Wainstein B, McCleary K, Nelson A, Gardiner B, Inam S, Badoux X, Ma K, Toro C, Hanna D, Hughes D, Conyers R, Cole T, Wang SS, Chee L, Fleming J, Irish A, Purtill D, Cooney J, Shaw P, Tey SK, Hunt S, Subramonia Pillai E, John G, Ng M, Ramachandran S, Hopkins P, Chambers D, Campbell S, Francis R, Isbel N, Marlton P, Reddiex H, Matthews KK, Voogt M, Panikkar A, Beagley L, Rehan S, Best S, Raju J, Le Texier L, Crooks P, Solomon M, Lekieffre L, Srihari S, Smith C, Khanna R.   +74 more
europepmc   +1 more source

Acute myeloid leukaemia cells secrete a soluble factor that inhibits T and NK cell proliferation but not cytolytic function – implications for the adoptive immunotherapy of leukaemia

, 2001
J. K. Orleans‐Lindsay, L D Barber, H. G. Prentice, Mark W. Lowdell   +3 more
openalex   +2 more sources

Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell-based anti-tumor immunotherapy [PDF]

, 2005
Claudia Wrzesinski, Nicholas P. Restifo
openalex   +1 more source

3‐Year Outcomes of Temperature‐Controlled Radiofrequency Ablation of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Temperature‐controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality of life (QoL). This study assesses the durability of TCRF's effectiveness and safety 3 years post‐procedure in patients with perennial allergic CR and nonallergic CR.
J. Pablo Stolovitzky, Randall A. Ow, Stacey L. Silvers, Bobby A. Tajudeen, Chad M. McDuffie, Marc Dean, Ahmad R. Sedaghat, Katie Phillips, Masayoshi Takashima   +8 more
wiley   +1 more source

Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity

Angewandte Chemie, EarlyView.
This study presents novel macrocyclic peptides with low nanomolar affinity for CD59, an immunomodulatory cell surface receptor associated with human disease. Crystallographic and structure‐activity relationship (SAR) studies reveal peptide CP‐06 mimics the binding of biologically relevant CD59 interaction partners. Dimeric and lipidated CP‐06 analogues
Jasmine K. Bickel, Ammar. I. S. Ahmed, Aidan B. Pidd, Rhodri M. Morgan, Tom E. McAllister, Sam Horrell, Emma C. Couves, Hemavathi Nagaraj, Edward J. Bartlett, Kamel El Omari, Akane Kawamura, Doryen Bubeck, Edward W. Tate   +12 more
wiley   +2 more sources

Bioceramics Enhance the Anti-Tumor Activity of Immune Cells in Adoptive Immunotherapy. [PDF]

Int J Mol Sci
Nose M, Nitta A, Zheng Y, Kizukuri R, Nagao Y, Nagai S, Aizawa M.   +6 more
europepmc   +1 more source

FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma. [PDF]

Mol Ther, 2023
Conde E, Casares N, Mancheño U, Elizalde E, Vercher E, Capozzi R, Santamaria E, Rodriguez-Madoz JR, Prosper F, Lasarte JJ, Lozano T, Hervas-Stubbs S.   +11 more
europepmc   +1 more source

Adoptive Immunotherapy against Experimental Visceral Leishmaniasis with CD8⁺T Cells Requires the Presence of Cognate Antigen [PDF]

, 2005
Rosalind Polley, Simona Stäger, Sara R. Prickett, Asher Maroof, Soombul Zubairi, Deborah F. Smith, Paul M. Kaye   +6 more
openalex   +1 more source

Do Skin Prick Tests Predict Nasal Provocation Test Outcomes in Allergic Rhinitis Patients?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background In diagnosing allergic rhinitis (AR), conventional skin prick tests (SPTs) often fail to reflect allergen‐induced nasal symptoms. Conversely, nasal provocation tests (NPTs) provide more definitive assessments but are less accessible.
Yunhyung Lee, Gyu Tae Kim, Seo Jun Kang, Marn Joon Park   +3 more
wiley   +1 more source