Results 291 to 300 of about 326,995 (379)

MYC: The Guardian of Its Own Chaos

BioEssays, EarlyView.
MYC is an oncogene that drives tumorigenesis through enhanced transcription and replication. Paradoxically, MYC induces transcriptional and replicative stress and acts as a resilience factor against these stressors. We discuss how MYC balances these stressors to promote tumor growth while evading immune detection and propose strategies to target MYC ...
Abdallah Gaballa, Bastian Krenz, Leonie Uhl   +2 more
wiley   +1 more source

Characterization of atypical T cells generated during ex vivo expansion process for T cell-based adoptive immunotherapy. [PDF]

Front Immunol
Mercier-Letondal P, Kumar A, Marton C, Bonnefoy F, Fredon M, Boullerot L, Dehecq B, Adotévi O, Godet Y, Galaine J.   +9 more
europepmc   +1 more source

Exploiting Cytokine Secretion to Rapidly Produce Multivirus-specific T Cells for Adoptive Immunotherapy [PDF]

, 2008
Yuriko Fujita, Ann M. Leen, Jiali Sun, Yozo Nakazawa, Eric Yvon, Helen E. Heslop, Malcolm K. Brenner, Cliona M. Rooney   +7 more
openalex   +1 more source

Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform

Biotechnology and Bioengineering, EarlyView.
The comparative effects of Doxorubicin and Aloe vera on HepG2 spheroids grown in a microfluidic device are illustrated in the graphical abstract. In the upper panel, red markers indicate that Doxorubicin treatment primarily induces necrosis in the spheroids.
Atakan Tevlek, Gunes Kibar, Barbaros Cetin   +2 more
wiley   +1 more source

111: Lenalidomide Directly Upregulates NK (Natural Killer) Cell Trail and Granzyme B Expression: Implications for Adoptive NK Cell Immunotherapy following Allogeneic Hematopoietic Stem Cell Transplantation (HCT) [PDF]

, 2008
Sanjeeva Srivastava, Andreas Lundqvist, M Berg, Hisayuki Yokoyama, Ally K. Smith, J. Philip McCoy, Richard W. Childs   +6 more
openalex   +1 more source

Liver organoids: From 3D printing to biomedical applications

BMEMat, EarlyView.
A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi, Xin Han, Zheng Zhang, Jiangtao Xu, Guozhen Liu   +4 more
wiley   +1 more source

Cellular Immunotherapy for Neuroblastoma: A Review of Current Vaccine and Adoptive T Cell Therapeutics [PDF]

, 2009
Chrystal U. Louis, M.K. Brenner
openalex   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Adoptive immunotherapy of cancer using CD4+ T cells [PDF]

, 2009
Pawel Muranski, Nicholas P. Restifo
openalex   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

BMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang, Yefei Dai, Yujun Hou, Joshua Stein, Shichen Steven Lin, Chaochen Zhou, Yannan Hou, Rongrong Zhu, Ki‐Bum Lee, Letao Yang   +9 more
wiley   +1 more source