Results 301 to 310 of about 326,995 (379)

Adoptive immunotherapy for cancer: the next generation of gene‐engineered immune cells [PDF]

, 2009
Linda J. Berry, Maria Moeller, Phillip K. Darcy   +2 more
openalex   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

T-cell adoptive immunotherapy for BK nephropathy in renal transplantation. [PDF]

Transpl Infect Dis, 2020
Jahan S, Scuderi C, Francis L, Neller MA, Rehan S, Crooks P, Ambalathingal GR, Smith C, Khanna R, John GT.   +9 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

CD138-directed adoptive immunotherapy of chimeric antigen receptor (CAR)-modified T cells for multiple myeloma

, 2016
Bo Guo, Meixia Chen, Qing-wang Han, F. Hui, Hanren Dai, Wen-ying Zhang, Yajing Zhang, Yao Wang, Hongli Zhu, W. Han   +9 more
semanticscholar   +1 more source

Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes.

Journal of Allergy and Clinical Immunology, 2016
Swati Naik, Swati Naik, S. Nicholas, C. Martinez, C. Martinez, A. Leen, P. Hanley, S. Gottschalk, C. Rooney, I. C. Hanson, R. Krance, E. Shpall, C. Cruz, P. Amrolia, G. Lucchini, N. Bunin, J. Heimall, O. Klein, A. Gennery, M. Slatter, M. Vickers, M. Vickers, J. Orange, H. Heslop, H. Heslop, C. Bollard, M. Keller   +26 more
semanticscholar   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

Cancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng, Shuang Zhang, Liang Han, Lin Wu, Jun Chen, Peiyan Zhao, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, Tamar Melkadze, Yueyin Pan, Xuhong Min, Maksym Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Haoyu Yu, Jing Li, Fang Yang, Xinyi Yang, Chen Ling, Qingyu Wang, Yongqiang Shan, Jun Zhu, the ASTRUM‐005 Study Group   +32 more
wiley   +1 more source

Development of CAR-T Cell Persistence in Adoptive Immunotherapy of Solid Tumors. [PDF]

Front Oncol, 2020
Fan J, Das JK, Xiong X, Chen H, Song J.
europepmc   +1 more source