Results 301 to 310 of about 306,104 (338)
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Chemo-immunotherapy and chemo-adoptive immunotherapy of cancer
Cancer Treatment Reviews, 2001The chemo-immunotherapy (CIT) and chemo-adoptive immunotherapy (CAIT) regimens tested in the past decade are summarized. From them we have learned a great deal about the interactions between various chemotherapeutic agents, immune modulating agents and effector cells.
R.B Hutchison, G.G Gomez, C.A Kruse
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Adoptive Immunotherapy for Malignant Glioma
The Cancer Journal, 2003Despite remarkable advancements in imaging modalities and treatment options available to patients diagnosed with malignant brain tumors, the prognosis for those with high-grade lesions remains poor. The imprecise mechanisms of currently available treatments to manage these tumors do not spare damage to the normal surrounding brain and often result in ...
John H. Sampson +2 more
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Adoptive Immunotherapy in Chimeras [PDF]
, 2003 Depletion of T-cells from the marrow by treatment with absorbed antithymocyte globulin (ATG) prevents GVHD in DLA-identical littermates and transfusion of donor lymphocytes on days 1 and 2, 21 and 22 induces fatal GVHD. However transfusion on days 61 and 62 dose not produce GVHD and the animals survive.
Martin Weber +9 more
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Adoptive Immunotherapy for Hodgkin's Lymphoma
International Journal of Hematology, 2006Adoptive transfer of tumor-specific T-cells is an attractive strategy for the treatment of patients with refractory or relapsed Hodgkin's lymphoma. However, Hodgkin's lymphomas possess a range of tumor-evasion mechanisms, which must be overcome before the full potential of immunotherapies can be achieved.
Catherine M. Bollard +2 more
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Adoptive immunotherapy of urologic tumors
1989The treatment of humans with advanced cancer represents a major therapeutic challenge. One approach to treating metastatic cancer is immunotherapy, which can be classified into active and passive categories. Active immunotherapy refers to the immunization of the tumor-bearing host with materials that attempt to induce in the host a state of immune ...
Steven A. Rosenberg, Arie S. Belldegrun
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Adoptive immunotherapy of HCMV infection
Cytotherapy, 2007Human cytomegalovirus (HCMV) infection or reactivation is a frequent cause of morbidity and mortality in immunocompromised individuals such as transplant recipients. Primary HCMV infection or reactivation of HCMV from latency is mostly asymptomatic in immunocompetent individuals and is controlled by the host's cell-mediated immune response.
Götz Ulrich Grigoleit +3 more
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Enhancing adoptive immunotherapy of cancer
Expert Opinion on Biological Therapy, 2010Conventional therapies, including surgery, chemotherapy and radiotherapy have contributed much to cancer treatment. However, these treatment modalities fail in a large proportion of patients, and there is a great need for effective alternate therapies.
Phillip K. Darcy +6 more
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Mononuclear Cell Adoptive Immunotherapy
Hematology/Oncology Clinics of North America, 1994In contrast with red cells, platelets, and granulocytes, hemotherapy using lymphocytes and monocytes is only beginning to be explored. Blood banks and transfusion services, the traditional sources of expertise in sterile cell processing, storage, and transfusion, have played an integral role in the early technical development of mononuclear cell ...
Harvey G. Klein, Jong-Hoon Lee
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Adoptive Immunotherapy of Melanoma
2011Adoptive immunotherapy involves the ex vivo manipulation and expansion of lymphocytes to treat cancer. These lymphocytes, or effector cells, are “adoptively” transferred into the recipient and may be infused alone or as part of a regimen that includes chemotherapy, radiation therapy, exogenous cytokines and/or other biologic agents (e.g., antibodies ...
Seth M. Pollack, Cassian Yee
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2004
Adoptive transfer originally referred to the ability to confer protective immunity on a naive host via infusion of T lymphocytes from an immune donor. This term now also encompasses a strategy of cancer therapy in which autologous T cells are acquired from a tumor-bearing host then activated and numerically expanded ex vivo prior to reinfusion.
Gregory E. Plautz +3 more
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Adoptive transfer originally referred to the ability to confer protective immunity on a naive host via infusion of T lymphocytes from an immune donor. This term now also encompasses a strategy of cancer therapy in which autologous T cells are acquired from a tumor-bearing host then activated and numerically expanded ex vivo prior to reinfusion.
Gregory E. Plautz +3 more
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