Results 311 to 320 of about 326,995 (379)

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Cancer Communications, EarlyView.
Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding   +20 more
wiley   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El‐Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Label‐Free Photonic Biosensors: Key Technologies for Precision Diagnostics

ChemistryEurope, EarlyView.
Photonic biosensors are versatile technologies promising unique advantages to improve current diagnosis workflows. On‐going research is directed to systems integration and automation as well as enhancing assay performance. Advances in bioengineering, material sciences, and photonics engineering will be the key toward their eventual implementation as ...
Maria Soler, Laura M. Lechuga
wiley   +1 more source

Genome-Editing Technologies in Adoptive T Cell Immunotherapy for Cancer

Current Hematologic Malignancy Reports, 2017
Nathan Singh, Junwei Shi, C. June, M. Ruella   +3 more
semanticscholar   +1 more source

Expanding the Horizons of Phototherapy: A Review on the Superior Performance of Chalcogen‐Based Photosensitizers and Photothermal Agents for Cancer Therapy

ChemPhotoChem, EarlyView.
This review summarizes recent progress in chalcogen (S, Se, Te)‐incorporated photosensitizers and photothermal agent design. It explores synthetic strategies, spectroscopic and computational characterization, and in vitro/in vivo evaluations, showcasing the potential of these compounds for photodynamic and photothermal therapies.
Subhrakant Jena, Pranay Mohanty, Laxmipriya Dash, Himansu S. Biswal   +3 more
wiley   +1 more source

Standardization of Suspension and Imaging Mass Cytometry Single‐Cell Readouts for Clinical Decision Making

Cytometry Part A, EarlyView.
ABSTRACT Suspension and imaging mass cytometry are single‐cell, proteomic‐based methods used to characterize tissue composition and structure. Data assessing the consistency of these methods over an extended period of time are still sparse and are needed if mass cytometry‐based methods are to be used clinically.
Ruben Casanova, Shuhan Xu, Pierre Bost, Sujana Sivapatham, Andrea Jacobs, Stefanie Engler, Tumor Profiler Consortium, Rudolf Aebersold, Melike Ak, Faisal S Al‐Quaddoomi, I Albert Silvana, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per‐Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck‐Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Lars Bosshard, Byron Calgua, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Ricardo Coelho, Maya D’Costa, Esther Danenberg, Natalie R Davidson, Monica‐Andreea Drăgan, Reinhard Dummer, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro F Ferreira, Joanna Ficek‐Pascual, Anja L Frei, Bruno Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann‐Schwarz, Sylvia Herter, Rene Holtackers, Tamara Huesser, Alexander Immer, Anja Irmisch, Francis Jacob, Andrea Jacobs, Tim M Jaeger, Katharina Jahn, Alva R James, Philip M Jermann, André Kahles, Abdullah Kahraman, Viktor H Koelzer, Werner Kuebler, Jack Kuipers, Christian P Kunze, Christian Kurzeder, Kjong‐Van Lehmann, Mitchell Levesque, Ulrike Lischetti, Flavio C Lombardo, Sebastian Lugert, Gerd Maass, Markus G Manz, Philipp Markolin, Martin Mehnert, Julien Mena, Julian M Metzler, Nicola Miglino, Emanuela S Milani, Holger Moch, Simone Muenst, Riccardo Murri, Charlotte KY Ng, Stefan Nicolet, Marta Nowak, Monica Nunez Lopez, Patrick GA Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Laurie Prélot, Natalie Rimmer, Mathilde Ritter, Christian Rommel, María L Rosano‐González, Gunnar Rätsch, Natascha Santacroce, Jacobo Sarabia del Castillo, Ramona Schlenker, Petra C Schwalie, Severin Schwan, Tobias Schär, Gabriela Senti, Wenguang Shao, Franziska Singer, Sujana Sivapatham, Berend Snijder, Bettina Sobottka, Vipin T Sreedharan, Stefan Stark, Daniel J Stekhoven, Tanmay Tanna, Alexandre PA Theocharides, Tinu M Thomas, Markus Tolnay, Vinko Tosevski, Nora C Toussaint, Mustafa A Tuncel, Marina Tusup, Audrey Van Drogen, Marcus Vetter, Tatjana Vlajnic, Sandra Weber, Walter P Weber, Rebekka Wegmann, Michael Weller, Fabian Wendt, Norbert Wey, Andreas Wicki, Mattheus HE Wildschut, Bernd Wollscheid, Shuqing Yu, Johanna Ziegler, Marc Zimmermann, Martin Zoche, Gregor Zuend, Mitchell P. Levesque, Reinhard Dummer, Bernd Bodenmiller, Stéphane Chevrier   +141 more
wiley   +1 more source

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

Electrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Deciphering the Potential Causal and Prognostic Relationships Between Gut Microbiota and Brain Tumors: Insights from Genetics Analysis and Machine Learning

Exploration, EarlyView.
The causal relationship between gut microbiota and brain tumors and potential prognostic value of microbiota are still unclear. This study confirmed the causal effects of specific gut microbiota on three common brain tumors and identified microbe‐related genes that are expressed in brain tissue and correlated with the abundance of gut microbiota ...
Changwu Wu, Fushu Luo, Yongye Zhu, Chunbo Liu, Zheng Chen, Xiangyu Wang, Jun Tan, Qing Liu   +7 more
wiley   +1 more source