Results 141 to 150 of about 3,533 (177)

ADP-Ribosyl Cyclase in Rat Salivary Glands

Biochemical and Biophysical Research Communications, 2000
Both the Ca(2+)-releasing mechanism induced by cyclic ADP-ribose (cADPR) and the ADP-ribosyl cyclase (ADPRC) activity that converts NAD(+) to cADPR were observed in a variety of cell types. We studied the ADPRC activity in rat major salivary glands that include parotid gland (PG), submandiblar gland (SMG), and sublingual gland (SLG).
Wataru Masuda, Tomoo Noguchi
exaly   +3 more sources

Structural Studies of Intermediates along the Cyclization Pathway of Aplysia ADP-Ribosyl Cyclase

Journal of Molecular Biology, 2012
Cyclic ADP-ribose (cADPR) is a calcium messenger that can mobilize intracellular Ca²⁺ stores and activate Ca²⁺ influx to regulate a wide range of physiological processes. Aplysia cyclase is the first member of the ADP-ribosyl cyclases identified to catalyze the cyclization of NAD⁺ into cADPR.
Graeff, R, Chen, Z, Hao, Q, Kotaka, M, Lee, HC, Zhang, LH   +5 more
openaire   +5 more sources

Mono(ADP-ribosyl)ation of Gi by eukaryotic cysteine-specific mono(ADP-ribosyl)transferase attenuates inhibition of adenylate cyclase by epinephrine

Biochimica Et Biophysica Acta - Molecular Cell Research, 1989
Eukaryotic cysteine-specific mono(ADP-ribosyl)transferase, named ADP-ribosyltransferase C (Tanuma, S., Kawashima, K. and Endo, H. (1988) J. Biol. Chem. 263, 5485-5489), attenuates inhibition of adenylate cyclase in human platelet membranes by epinephrine. This attenuation appeared to result from mono(ADP-ribosyl)ation by ADP-ribosyltransferase C of the
S Tanuma, Hiroyoshi Endo
exaly   +3 more sources

Subcellular localization of cyclic ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities in porcine airway smooth muscle

Biochimica Et Biophysica Acta - Molecular Cell Research, 2000
Recent studies have provided evidence for a role of cyclic ADP-ribose (cADPR) in the regulation of intracellular calcium in smooth muscles of the intestine, blood vessels and airways.
Thomas A White, Timothy F Walseth, Cheung Lee   +2 more
exaly   +2 more sources

Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells: Intracellular concentration decrease in NAD and increase in cyclic ADP-ribose

FEBS Letters, 2006
ADP-ribosyl cyclase activity in the crude membrane fraction of neuroblastoma×glioma NGPM1-27 hybrid cells was measured by monitoring [3H] cyclic ADP-ribose (cADPR) formation from [3H] NAD+.
Haruhiro Higashida, Alla Salmina, Minako Hashii   +2 more
exaly   +4 more sources

ADP ribosyl cyclase activity of a novel bone marrow stromal cell surface molecule, BST-1

FEBS Letters, 1994
Human BST-1, a bone marrow stromal cell surface molecule, is a GPI-anchored protein that facilitates the growth of pre-B cells. The deduced amino acid sequences of human and mouse BST-1 show around 30% homology with those of CD38 and Aplysia ADP ribosyl ...
Y Hirata, Yoshiyuki Ohsugi, Shin Takasawa   +2 more
exaly   +2 more sources

Oscillation of ADP-ribosyl cyclase activity during the cell cycle and function of cyclic ADP-ribose in a unicellular organism, Euglena gracilis

FEBS Letters, 1997
In Euglena gracilis, the activity of ADP-ribosyl cyclase, which produces cyclic ADP-ribose, oscillated during the cell cycle in a synchronous culture induced by a light-dark cycle, and a marked increase in the activity was observed in the G2 phase ...
Wataru Masuda, Hiroshi Nishina, Shingo Tsuyama   +2 more
exaly   +2 more sources

Oxytocin-induced elevation of ADP-ribosyl cyclase activity, cyclic ADP-riboseor Ca2+ concentrations is involved in autoregulation of oxytocin secretionin the hypothalamus and posterior pituitary in male mice

Neuropharmacology, 2010
Locally released oxytocin (OT) activates OT receptors (2.1:OXY:1:OT:) in neighboring neurons in the hypothalamus and their terminals in the posterior pituitary, resulting in further OT release, best known in autoregulation occurring during labor or milk ...
Olga Lopatina, Hong-Xiang Liu, Minako Hashii   +2 more
exaly   +3 more sources

Role of kidney ADP-ribosyl cyclase in diabetic nephropathy

American Journal of Physiology-Renal Physiology, 2009
The role of ADP-ribosyl cyclases (ADPR-cyclases) in diabetic nephropathy was investigated. ADPR-cyclases synthesize cADP-ribose (cADPR), a Ca2+-mobilizing second messenger, and are stimulated by G protein-coupled receptors. We have previously reported that ADPR-cyclases can be activated by ANG II and showed that a specific kidney ADPR-cyclase inhibitor,
Seon-Young, Kim, Kwang-Hyun, Park, Rukhsana, Gul, Kyu Yoon, Jang, Uh-Hyun, Kim   +4 more
openaire   +2 more sources

ADP ribosyl-cyclases (CD38/CD157), social skills and friendship

Psychoneuroendocrinology, 2017
Why some individuals seek social engagement while others shy away has profound implications for normal and pathological human behavior. Evidence suggests that oxytocin (OT), the paramount human social hormone, and CD38 that governs OT release, contribute to individual differences in social skills from intense social involvement to extreme avoidance ...
Anne, Chong, Fabio, Malavasi, Salomon, Israel, Chiea Chuen, Khor, Von Bing, Yap, Mikhail, Monakhov, Soo Hong, Chew, Poh San, Lai, Richard P, Ebstein   +8 more
openaire   +2 more sources