Class I ADP-ribosylation factors are involved in enterovirus 71 replication. [PDF]
PLoS ONE, 2014 Enterovirus 71 is one of the major causative agents of hand, foot, and mouth disease in infants and children. Replication of enterovirus 71 depends on host cellular factors.
Jianmin Wang, Jiang Du, Qi Jin
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Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. [PDF]
J Biol Chem, 2012 Background: To date, very few cellular factors required for secretion of flaviviruses have been described. Results: Simultaneous depletion of class II Arf (Arf4 and Arf5) blocks dengue flavivirus secretion, without altering the constitutive secretory ...
Kudelko M +9 more
europepmc +7 more sources
Structure, organization and evolution of ADP-ribosylation factors in rice and foxtail millet, and their expression in rice. [PDF]
Sci Rep, 2016 ADP-ribosylation factors (ARFs) have been reported to function in diverse physiological and molecular activities. Recent evidences also demonstrate the involvement of ARFs in conferring tolerance to biotic and abiotic stresses in plant species.
Muthamilarasan M +4 more
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Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling [PDF]
Nature Communications, 2023 In the mammalian DNA damage response, ADP-ribosylation signalling is of crucial importance to mark sites of DNA damage as well as recruit and regulate repairs factors.
Pietro Fontana +9 more
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MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors. [PDF]
Cell Microbiol, 2016 Vibrio vulnificus infects humans and causes lethal septicemia. The primary virulence factor is a multifunctional‐autoprocessing repeats‐in‐toxin (MARTX) toxin consisting of conserved repeats‐containing regions and various effector domains. Recent genomic
Kim BS, Satchell KJ.
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Genome-wide identification and expression analysis of ADP-ribosylation factors associated with biotic and abiotic stress in wheat (Triticum aestivum L.) [PDF]
PeerJ, 2021 The ARF gene family plays important roles in intracellular transport in eukaryotes and is involved in conferring tolerance to biotic and abiotic stresses in plants. To explore the role of these genes in the development of wheat (Triticum aestivum L.), 74
Yaqian Li +8 more
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Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription [PDF]
Scientific Reports, 2018 Macrodomains are conserved protein folds associated with ADP-ribose binding and turnover. ADP-ribosylation is a posttranslational modification catalyzed primarily by ARTD (aka PARP) enzymes in cells.
Mareike Bütepage +15 more
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Rapid evolution of PARP genes suggests a broad role for ADP-ribosylation in host-virus conflicts. [PDF]
PLoS Genetics, 2014 Post-translational protein modifications such as phosphorylation and ubiquitinylation are common molecular targets of conflict between viruses and their hosts. However, the role of other post-translational modifications, such as ADP-ribosylation, in host-
Matthew D Daugherty +3 more
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ARNO Is a Guanine Nucleotide Exchange Factor for ADP-ribosylation Factor 6 [PDF]
Journal of Biological Chemistry, 1998 ADP-ribosylation factors (ARFs) constitute a family of small monomeric GTPases. ARFs 1 and 3 function in the recruitment of coat proteins to membranes of the Golgi apparatus, whereas ARF6 is localized to the plasma membrane, where it appears to modulate both the assembly of the actin cytoskeleton and endocytosis.
Scott R. Frank +3 more
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Dispensability of HPF1 for cellular removal of DNA single-strand breaks. [PDF]
Nucleic Acids ResIn response to DNA damage, the histone PARylation factor 1 (HPF1) regulates PARP1/2 activity, facilitating serine ADP-ribosylation of chromatin-associated factors.
Hrychova K +9 more
europepmc +3 more sources