Class I ADP-ribosylation factors are involved in enterovirus 71 replication. [PDF]
PLoS ONE, 2014 Enterovirus 71 is one of the major causative agents of hand, foot, and mouth disease in infants and children. Replication of enterovirus 71 depends on host cellular factors.
Jianmin Wang, Jiang Du, Qi Jin
doaj +4 more sources
Genome-wide identification and expression analysis of ADP-ribosylation factors associated with biotic and abiotic stress in wheat (Triticum aestivum L.) [PDF]
PeerJ, 2021 The ARF gene family plays important roles in intracellular transport in eukaryotes and is involved in conferring tolerance to biotic and abiotic stresses in plants. To explore the role of these genes in the development of wheat (Triticum aestivum L.), 74
Yaqian Li +8 more
doaj +3 more sources
Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. [PDF]
J Biol Chem, 2012 This article is available open access through the publisher’s website.Identification and characterization of virus-host interactions are very important steps toward a better understanding of the molecular mechanisms responsible for disease progression ...
Kudelko M +9 more
europepmc +8 more sources
ADP-Ribosylation Factor Family of Small GTP-Binding Proteins: Their Membrane Recruitment, Activation, Crosstalk and Functions [PDF]
Frontiers in Cell and Developmental Biology, 2022 Members of the ADP-ribosylation factor (ARF) family of guanine-nucleotide binding proteins play critical roles in various cellular processes, especially in regulating the secretory, and endocytic pathways.
Tiantian Li +3 more
doaj +2 more sources
ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs [PDF]
Frontiers in Molecular BiosciencesADP-ribosylation factors (ARFs) are GTP-binding proteins that were discovered in the early 1980s, shortly after heterotrimeric GTP-binding proteins (G proteins) and nearly simultaneously with RAS.
Rachel E. Turn +5 more
doaj +2 more sources
Nature Communications, 2023 In the mammalian DNA damage response, ADP-ribosylation signalling is of crucial importance to mark sites of DNA damage as well as recruit and regulate repairs factors.
Pietro Fontana +9 more
doaj +1 more source
In Vivo Models and In Vitro Assays for the Assessment of Pertussis Toxin Activity
Toxins, 2021 One of the main virulence factors produced by Bordetella pertussis is pertussis toxin (PTx) which, in its inactivated form, is the major component of all marketed acellular pertussis vaccines.
Marieke Esther Hoonakker
doaj +1 more source
Rapid evolution of PARP genes suggests a broad role for ADP-ribosylation in host-virus conflicts. [PDF]
PLoS Genetics, 2014 Post-translational protein modifications such as phosphorylation and ubiquitinylation are common molecular targets of conflict between viruses and their hosts. However, the role of other post-translational modifications, such as ADP-ribosylation, in host-
Matthew D Daugherty +3 more
doaj +1 more source
ARF6 controls RHOB targeting to endosomes regulating cancer cell invasion
Molecular & Cellular Oncology, 2020 Endocytic trafficking has emerged as an essential mechanism to spatiotemporally coordinate signaling protein complexes that control cytoskeletal dynamics and cell motility. Our study established an unexpected regulatory mechanism whereby ADP ribosylation
Kossay Zaoui +3 more
doaj +1 more source
EFA6 in Axon Regeneration, as a Microtubule Regulator and as a Guanine Nucleotide Exchange Factor
Cells, 2021 Axon regeneration after injury is a conserved biological process that involves a large number of molecular pathways, including rapid calcium influx at injury sites, retrograde injury signaling, epigenetic transition, transcriptional reprogramming ...
Gilberto Gonzalez, Lizhen Chen
doaj +1 more source