Results 101 to 110 of about 45,797 (235)
Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities [PDF]
, 2013 Poly-ADP-ribosylation is a post-translational modification that regulates processes involved in genome stability. Breakdown of the poly(ADP-ribose) (PAR) polymer is catalysed by poly(ADP-ribose) glycohydrolase (PARG), whose endo-glycohydrolase activity ...
Ahel, Ivan +10 more
core +2 more sources
Traffic jam on the cellular secretory pathway generated by a replication protein from a plant RNA virus [PDF]
, 2014 Although positive-strand RNA [(+)RNA] viruses have a limited coding capacity, they can replicate efficiently in host cells because of their ability to use host-derived proteins, membranes, lipids, and metabolites, and to rewire cellular trafficking ...
Hyodo, Kiwamu +2 more
core +1 more source
Frontiers in MicrobiologySARS-CoV-2 reprograms host cell biology not solely through its genomic content but also through a sophisticated arsenal of post-translational modifications (PTMs) that modulate viral protein function, host signaling networks, and immune responses ...
Jie Qu, Minglong Liu, Chen Zhou
doaj +1 more source
Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
PLoS ONE, 2012 BackgroundAlthough the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1) has been reported, its function in neural crest development is unclear.Methods/principal findingsWe found that knockdown of Arl6ip1 ...
Chi-Tang Tu +3 more
doaj +1 more source
The RST and PARP-like domain containing SRO protein family: analysis of protein structure, function and conservation in land plants [PDF]
, 2010 Peer ...
Pinja Jaspers +7 more
core +1 more source
Mapping genetic interactions in cancer: a road to rational combination therapies. [PDF]
, 2019 The discovery of synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) inhibitors and BRCA genes, which are involved in homologous recombination, led to the approval of PARP inhibition as a monotherapy for patients with BRCA1/2 ...
Krogan, Nevan J, Tutuncuoglu, Beril
core
Golgicide A Reveals Essential Roles for GBF1 in Golgi Assembly and Function [PDF]
, 2013 ADP-ribosylation factor 1 (Arf1) plays a critical role in regulating secretory traffic and membrane transport within the Golgi of eukaryotic cells. Arf1 is activated by guanine nucleotide exchange factors (ArfGEFs) which confer spatial and temporal ...
Bursulaya, Badry +6 more
core +1 more source
, 2019 In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
core +1 more source
リンパ管新生における低分子量Gタンパク質Arf6の機能 [PDF]
, 2017 筑波大学 (University of Tsukuba ...
Lin Yueh-Chien, 林 岳謙
core +1 more source
A Commander-independent function of COMMD3 in endosomal trafficking
eLifeEndosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradation in lysosomes.
Galen T Squiers +4 more
doaj +1 more source