Results 111 to 120 of about 213,935 (349)

The Guanine Nucleotide Exchange Factor ARNO mediates the activation of ARF and phospholipase D by insulin

BMC Cell Biology, 2003
Background Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanism of activation of PLD and ARF by ...
Fluharty Eric, Vasudevan Chandrasekaran, Rizzo Mark A, Rojas Raúl, Shome Kuntala, Li Hai-Sheng, Santy Lorraine C, Casanova James E, Romero Guillermo   +8 more
doaj   +1 more source

Factorizations of almost simple groups with a factor having many nonsolvable composition factors [PDF]

arXiv, 2017
This paper classifies the factorizations of almost simple groups with a factor having at least two nonsolvable composition factors. This together with a previous classification result of the authors reduces the factorization problem of almost simple groups to the case where both factors have a unique nonsolvable composition factor.
arxiv  

Identification of Arfophilin, a Target Protein for GTP-bound Class II ADP-ribosylation Factors*

Journal of Biological Chemistry, 1999
Yeast two-hybrid screening of a human kidney cDNA library using the GTP-bound form of a class II ADP-ribosylation factor (ARF5) identified a novel ARF5-binding protein with a calculated molecular mass of 82.4 kDa, which was named arfophilin.
O. Shin, A. Ross, Irene Mihai, J. Exton
semanticscholar   +1 more source

Characterization and Chromosome Location of ADP-ribosylation Factors (ARFs) in Wheat

Pakistan Journal of Biological Sciences, 2014
In this study, the ARF genes were cloned, sequenced and located on the chromosomes. The gene expression of various stress conditions were analyzed through RT-PCR. Two important features of ARF in wheat were found: (1) High sequences homology among species in mammalian and plant and (2) Four exons and three introns were conserved in Poaceae.
Guoyue Chen, Yu-Ming Wei, Shou-Fen Dai, Xiujing Lan, Qiantao Jiang, Li Wei, Jirui Wang, Ya-Xi Liu, Zhien Pu, You-Liang Zheng   +9 more
openaire   +3 more sources

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

SIRT6 promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer

FEBS Open Bio, 2022
Ovarian cancer ranks fifth in terms of cancer mortality in women due to lack of early diagnosis and poor clinical management. Characteristics like high cellular proliferation, EMT and metabolic alterations contribute to oncogenicity.
Shreya Bandopadhyay, Parash Prasad, Upasana Ray, Damayanti Das Ghosh, Sib Sankar Roy   +4 more
doaj   +1 more source

The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The human peptidyl‐prolyl‐cis/trans isomerases (PPIases), Parvulin 14 and Parvulin 17, accelerate the cis/trans isomerization of Xaa‐Pro moieties within protein sequences. By modulating the respective binding interfaces of their target proteins, they play a crucial role in determining the fate of their substrates within the cell. Although both
Anna Sternberg, Jennifer Lynne Borger, Mathilda Thies, Anja Matena, Mike Blueggel, Bianca E. Kamba, Christine Beuck, Farnusch Kaschani, Markus Kaiser, Peter Bayer   +9 more
wiley   +1 more source

Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast. [PDF]

PLoS ONE, 2013
Membrane trafficking is essential to eukaryotic life and is controlled by a complex network of proteins that regulate movement of proteins and lipids between organelles.
Alan M Eckler, Caroline Wilder, Antonio Castanon, Veronica M Ferris, Rachael A Lamere, Benjamin A Perrin, Ross Pearlman, Blaise White, Clifton Byrd, Nicholas Ludvik, Nona Nichols, Kristen Poole-Sumrall, Elizabeth Sztul, Melanie L Styers   +13 more
doaj   +1 more source

Phosphoinositides determine specificity of the guanine-nucleotide exchange activity of cytohesin-1 for ADP-ribosylation factors derived from a mammalian expression system.

European Journal of Biochemistry, 2000
ADP-ribosylation factors (ARFs) are small Ras-like GTPases which play important roles in intracellular vesicle transport and in the remodeling of the actin cytoskeleton.
T. Knorr, Wolfgang Nagel, Waldemar Kolanus   +2 more
semanticscholar   +1 more source

Site-specific ADP-ribosylation of histone H2B in response to DNA 2 double strand breaks [PDF]

, 2017
ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins
Hsu, Duen-Wei, Lakin, Nicholas, Pears, Catherine J., Rakhimova, Alina, Ura, Seiji, Wang, Hong-Yu   +5 more
core   +2 more sources