Results 121 to 130 of about 213,935 (349)
A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly
Small Methods, EarlyView.ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan +5 more
wiley +1 more source
Scientific Reports, 2021 Phytophthora nicotianae is highly pathogenic to Solanaceous crops and is a major problem in tobacco production. The tobacco cultivar Beihart1000-1 (BH) is resistant, whereas the Xiaohuangjin 1025 (XHJ) cultivar is susceptible to infection.
He Meng +13 more
doaj +1 more source
Some Results on Factorization of Monoids [PDF]
arXiv, 2022 Factorizations of monoids are studied. Two necessary and sufficient conditions in terms of so-called descent 1-cocyles for a monoid to be factorized through two submonoids are found. A full classification of those factorizations of a monoid whose one factor is a subgroup of the monoid is obtained.
arxiv
Heregulin promotes expression and subcellular redistribution of ADP‐ribosylation factor 3
FEBS Letters, 2002 To identify genes whose expression is modulated by heregulin‐β1 (HRG), a regulatory polypeptide for mammary epithelial cells, we performed differential display screening of MCF‐7 cell mRNA. One cDNA clone upregulated by HRG was identical to human ADP‐ribosylation factor 3 (ARF3), a guanine nucleotide‐binding protein functioning in vesicular trafficking,
Christopher J. Barnes +4 more
openaire +3 more sources
Interpretable Sparse Proximate Factors for Large Dimensions [PDF]
arXiv, 2018 This paper proposes sparse and easy-to-interpret proximate factors to approximate statistical latent factors. Latent factors in a large-dimensional factor model can be estimated by principal component analysis (PCA), but are usually hard to interpret.
arxiv
Factor Investing with a Deep Multi-Factor Model [PDF]
arXiv, 2022 Modeling and characterizing multiple factors is perhaps the most important step in achieving excess returns over market benchmarks. Both academia and industry are striving to find new factors that have good explanatory power for future stock returns and good stability of their predictive power.
arxiv
Identification and Roles of Cell Substrates of Intracellular Mono-ADP-Ribosylation [PDF]
, 2012 Mono-ADP-ribosylation is a reversible post-translational modification that is catalysed by either bacterial pathogenic toxins or endogenous cellular ADP- ribosyltransferases (ARTs), and that can modulate the functions of target proteins.
Grimaldi, Giovanna
core +1 more source
ADP-ribosylation factor is functionally and physically associated with the Golgi complex. [PDF]
Proceedings of the National Academy of Sciences, 1990 ADP-ribosylation factor (ARF) is a ubiquitous, highly conserved 21-kDa GTP-binding protein, first identified in animal cells as the cofactor required for the in vitro ADP-ribosylation of the stimulatory regulatory subunit of adenylate cyclase, Gs, by cholera toxin.
David Botstein +3 more
openaire +3 more sources
Arrestin‐centred interactions at the membrane and their conformational determinants
British Journal of Pharmacology, EarlyView.Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood +3 more
wiley +1 more source
Frontiers in Plant Science, 2016 Shikonin derivatives are specialized lipophilic metabolites, secreted in abundant amounts from the root epidermal cells of Lithospermum erythrorhizon.
Kanade Tatsumi +8 more
doaj +1 more source