Results 91 to 100 of about 53,577 (232)
Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. [PDF]
, 2017 Cool-associated tyrosine-phosphorylated protein 1 (Cat-1) is a signaling scaffold as well as an ADP-ribosylation factor-GTPase-activating protein. Although best known for its role in cell migration, we recently showed that the ability of Cat-1 to bind ...
Antonyak, Marc A. +3 more
core +2 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk +15 more
wiley +1 more source
PLoS ONE, 2012 BackgroundARF6 (ADP-ribosylation factor 6) small GTP binding protein plays critical roles in actin cytoskeleton rearrangements and membrane trafficking, including internalisation of G protein coupled receptors (GPCR). ARF6 operates by cycling between GDP-
Venkateswarlu Kanamarlapudi +3 more
doaj +1 more source
ADP-Ribosylargininyl reaction of cholix toxin is mediated through diffusible intermediates [PDF]
, 2014 Background: Cholix toxin is an ADP-ribosyltransferase found in non-O1/non-O139 strains of Vibrio cholera. The catalytic fragment of cholix toxin was characterized as a diphthamide dependent ADP-ribosyltransferase.
Sung, Vicky M-H, Tsai, Chia-Lun
core +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
High-throughput screening assay for PARP-HPF1 interaction inhibitors to affect DNA damage repair
Scientific ReportsADP-ribosyltransferases PARP1 and PARP2 play a major role in DNA repair mechanism by detecting the DNA damage and inducing poly-ADP-ribosylation dependent chromatin relaxation and recruitment of repair proteins.
Saurabh S. Dhakar +2 more
doaj +1 more source
Fisheries and Aquatic Sciences, 2017 Small GTPases are well known as one of the signal transduction factors of immune systems. The ADP-ribosylation factors (ARFs) can be classified into three groups based on the peptide sequence, protein molecular weight, gene structure, and phylogenetic ...
So-Hee Son +4 more
doaj +1 more source
Proteomic Analysis of Cervicovaginal Fluid for Diagnostic Endometriosis Biomarker Discovery
PROTEOMICS – Clinical Applications, Volume 20, Issue 3, May 2026.ABSTRACT Purpose Endometriosis is a prevalent inflammatory condition characterised by the presence of endometrial‐like tissue outside the uterus and is associated with significant challenges, including diagnostic delays and continued reliance on laparoscopy.
Emily S. J. Paterson +7 more
wiley +1 more source
Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6
BMC Cell Biology, 2009 Background Peroxisomes execute diverse and vital functions in virtually every eukaryote. New peroxisomes form by budding from pre-existing organelles or de novo by vesiculation of the ER.
Mannaerts Guy P +9 more
doaj +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source