Results 111 to 120 of about 53,577 (232)

Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins [PDF]

, 2015
SummaryAs the key effector in the Hippo pathway, YAP was identified as an oncoprotein whose expression is elevated in various human cancers. However, the development of potentially therapeutic compounds targeting YAP has been slow and limited.
Wang, Wenqi, Li, Nan, Li, Xu, Tran, My Kim, Han, Xin, Chen, Junjie   +5 more
core   +4 more sources

ADP-Ribosylation Factor 6 Pathway Acts as a Key Executor of Mesenchymal Tumor Plasticity. [PDF]

Int J Mol Sci, 2023
Hashimoto A, Hashimoto S.
europepmc   +1 more source

The Chikungunya Virus nsP3 Macro Domain Inhibits Activation of the NF-κB Pathway

Viruses
The role of the chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in the virus lifecycle is poorly understood. The protein comprises three domains.
Grace C. Roberts, Nicola J. Stonehouse, Mark Harris   +2 more
doaj   +1 more source

The Sclerotinia sclerotiorum ADP-Ribosylation Factor 6 Plays an Essential Role in Abiotic Stress Response and Fungal Virulence to Host Plants. [PDF]

J Fungi (Basel), 2023
Wang K, Wang S, Wang T, Xia Q, Xia S.
europepmc   +1 more source

The Role and Antagonistic Effects of miR-16-5p in the Regulation of ADP-Ribosylation Factor-Like Tumor Suppressor Gene 1 in Lung Cancer Cells. [PDF]

Eurasian J Med, 2023
Yüksel TN, Bozgeyik E, Bozgeyik İ.
europepmc   +1 more source

ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development. [PDF]

eNeuro, 2023
Hara Y, Katsuyama T, Fukaya M, Sugawara T, Shiroshima T, Sadakata T, Osumi N, Sakagami H.   +7 more
europepmc   +1 more source

Correction: ADP Ribosylation Factor Like 2 (Arl2) Regulates Breast Tumor Aggressivity in Immunodeficient Mice.

PLoS ONE, 2009
Anne Beghin, Stéphane Belin, Rouba Hage-Sleiman, Stéphanie Brunet Manquat, Sophie Goddard, Eric Tabone, Lars P. Jordheim, Isabelle Treilleux, Marie-France Poupon, Jean-Jacques Diaz, Charles Dumontet   +10 more
doaj   +3 more sources

Thalamic Neuron Resilience during Osmotic Demyelination Syndrome (ODS) Is Revealed by Primary Cilium Outgrowth and ADP-ribosylation factor-like protein 13B Labeling in Axon Initial Segment. [PDF]

Int J Mol Sci, 2023
Gilloteaux J, De Swert K, Suain V, Nicaise C.   +3 more
europepmc   +1 more source

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins. [PDF]

J Biol Chem, 2023
Rosenberg EM, Jian X, Soubias O, Yoon HY, Yadav MP, Hammoudeh S, Pallikkuth S, Akpan I, Chen PW, Maity TK, Jenkins LM, Yohe ME, Byrd RA, Randazzo PA.   +13 more
europepmc   +1 more source

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1. [PDF]

J Biol Chem, 2022
Luciano AK, Korobkina ED, Lyons SP, Haley JA, Fluharty SM, Jung SM, Kettenbach AN, Guertin DA.   +7 more
europepmc   +1 more source