Results 1 to 10 of about 16,655 (259)

Cervical Artery Dissection in Autosomal Dominant Polycystic Kidney Disease [PDF]

Medicina
Background and Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multisystem involvement, including renal cysts, hepatic cysts, intracranial aneurysms, and aortic root dilatation and dissection. Though exceedingly rare,
Anna Liu, Helena Xeros, Waseem Wahood, Zafer Keser, Muhib Khan   +4 more
doaj   +2 more sources

Association of autosomal dominant polycystic kidney disease (ADPKD) with cardiovascular disease and mortality in patients with treated kidney failure [PDF]

BMC Nephrology
Introduction Autosomal dominant polycystic kidney disease (ADPKD) is a multisystem syndrome associated with significant morbidity and mortality, particularly kidney failure.
Julia Jefferis, Andrew J. Mallett, Gopi Rangan, Yeoungjee Cho, Andrea K. Viecelli, Venkat Vangaveti, David W. Johnson, Carmel M. Hawley   +7 more
doaj   +2 more sources

End Point Selection in ADPKD Clinical Trials [PDF]

Kidney International Reports
Autosomal dominant polycystic kidney disease (ADPKD) is the leading hereditary cause of kidney failure. Challenges have arisen in developing consensus-based clinical trial end points endorsed by the wider ADPKD research community and regulators.
Kitty St Pierre, Ragada El-Damanawi, Julia Jefferis, David W. Johnson, Carmel M. Hawley, Christine E. Staatz, Andrea K. Viecelli, Andrew J. Mallett   +7 more
doaj   +2 more sources

Safety and feasibility of synchronous unilateral nephrectomy and contralateral heminephrectomy for extremely severe autosomal dominant polycystic kidney disease: Techniques and outcome [PDF]

Investigative and Clinical Urology, 2022
Purpose: To demonstrate the safety and feasibility of synchronous unilateral nephrectomy and contralateral heminephrectomy in extremely severe autosomal dominant polycystic kidney disease (ADPKD), which corresponds to the Mayo imaging classification ...
Jang Hee Han, Seung-hwan Jeong, Hyeong Dong Yuk , Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Curie Ahn, Chang Wook Jeong   +7 more
doaj   +1 more source

Venglustat, Acetato de Lanreotida y Tolvaptan como opciones terapéuticas para el tratamiento de la enfermedad renal poliquística autosómica dominante: revisión narrativa

Interdisciplinary Journal of Epidemiology and Public Health, 2021
Introducción: la enfermedad poliquística renal autosómica (ADPKD), es considerada huérfana hereditaria. Con una prevalencia mundial de 2.7/100,000 hab. Presenta graves complicaciones con desenlaces fatales.
Juan Sebastian Valencia Quintero, Diana Castillo   +1 more
doaj   +1 more source

Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]

, 2004
Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould, Bhunia, Duyndam, Giles, Grotewold, Huan, Kim, Kimberling, Kugoh, Loghman-Adham, Löhning, Morin, Moser, Muto, Newby, Ouwens, Parnell, Peters, Pritchard, Rivat, Rodova, Saadi-Kheddouci, Scheffers, Shaulian, Smits, Sorenson, Spaargaren, Streets, Sutters, Trudel, Upadhya, van Adelsberg, van Dam, van Dam, van Dam, van Dam, van de Wetering, van de Wetering   +37 more
core   +17 more sources

Autosomal Dominant Polycystic Kidney Desease Coexisting with Renal Dysplasia. First Case Described and Followed Since Prenatal Period [PDF]

Childhood Kidney Diseases, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease and causes terminal chronic renal failure. ADPKD is characterized by bilateral multiple renal cysts, which are produced by mutations of the PKD1 and PKD2 ...
Carmen Truyols
doaj   +1 more source

Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression [PDF]

Kidney Research and Clinical Practice, 2022
Background Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases, is characterized by the presence of numerous fluid-filled renal cysts and is a leading cause of end-stage renal disease (ESRD).
Hyunsuk Kim, Jinmo Sung, Ju Young Bae, Poongyeon Lee, Yun Kyu Oh, Hyunho Kim   +5 more
doaj   +1 more source

The Relationship Between Dietary Intakes and Total Kidney Volume in Patients with Autosomal Dominant Polycystic Kidney Disease Dietary Intake and Polycystic Kidney Volume

Haseki Tıp Bülteni, 2022
Aim:There is a need to understand autosomal dominant polycystic kidney disease (ADPKD) patients’ dietary habits since dietary interventions may have potential effects on ADPKD.
Yonca Sevim, Egemen Cebeci, Ozlem Persil Ozkan, Yildiray Savas, Savas Ozturk, Gul Kiziltan   +5 more
doaj   +1 more source

Rapidly progressive nephromegaly in a neonate with autosomal recessive poly cystic kidney disease [PDF]

Journal of Nephropathology, 2017
Background: Autosomal recessive polycystic kidney disease (ARPKD) associates with significant renal and liver-related morbidity and mortality in children. Rarely severe enlargement of kidneys necessitates nephrectomy and initiating dialysis.
Mitra Naseri, Nona Zabolinejad, Syed Ali Alamdaran, Reza Shojaeian   +3 more
doaj   +1 more source