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Targeting Cyst Initiation in ADPKD [PDF]
Journal of the American Society of Nephrology, 2009 With approximately 12.5 million people worldwide affected by autosomal dominant polycystic kidney disease (ADPKD), one hopes we are now at the beginning of multiple therapeutic breakthroughs. ADPKD is a hereditary disorder caused by a genetic defect in either polycystin-1 ( PKD1 ; PC1) or polycystin-2 ( PKD2 ; PC2) that leads to progressive kidney cyst
Stephanie J. Leuenroth, Craig M. Crews
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Renal replacement therapy in ADPKD patients : a 25-year survey based on the Catalan registry [PDF]
, 2013 Background: Some 7-10% of patients on replacement renal therapy (RRT) are receiving it because of autosomal dominant polycystic kidney disease (ADPKD). The age at initiation of RRT is expected to increase over time.
Arcos, Emma +8 more
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Risk factors for progression in ADPKD
Current Opinion in Nephrology and Hypertension, 2015 Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. This article will describe the factors associated with both functional and structural evidence of disease progression. It will also review the results of recent clinical trials that have shown an impact on markers of disease progression.A variety of ...
Ahsan Alam
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Simultaneous laparoscopic nephrectomy in ADPKD
Journal of Minimal Access Surgery, 2010 MaheshR Desai +3 more
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Overweight and Obesity and Progression of ADPKD [PDF]
Clinical Journal of the American Society of Nephrology, 2021 Background and objectives On the basis of earlier observations, we evaluated the association between overweight and obesity and rapid progression of autosomal dominant polycystic kidney disease in participants in the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes ...
Kristen L. Nowak +5 more
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Antenatally Diagnosed ADPKD [PDF]
Kidney International Reports, 2018 [Extract] Advances in antenatal ultrasonographyhave substantially improved the counseling of pregnantwomen.1 4With this advancement comes a diagnosticdilemma in the approach to antenatal diagnoses of cystickidney disease. The differential diagnosis of enlargedcystic echogenic kidneys includes autosomal dominantpolycystic kidney disease (ADPKD ...
Aldridge, Melanie +3 more
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Advances in Kidney Disease and Health, 2023 Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. It has been associated with a significant physical and psychological burden, leading to a reduced quality of life. The purpose of this literature review is to summarize the patient perspective on ADPKD based on the current published literature.
Matthew Gittus +2 more
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Intrafamilial Variability of ADPKD [PDF]
Kidney International Reports, 2019 Discordance in kidney disease severity between affected relatives is a recognized feature of autosomal dominant polycystic kidney disease (ADPKD). Here, we report a systematic study of a large cohort of families to define the prevalence and clinical features of intrafamilial discordance in ADPKD.The extended Toronto Genetic Epidemiology Study of ...
Matthew B. Lanktree +25 more
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Recalcitrant pain in a patient with ADPKD [PDF]
Kidney International, 2009 Tinika A. Montgomery and Fred E. Yeo Department of Internal Medicine, National Naval Medical Center, Bethesda, Maryland, USA and Nephrology Department, National Naval Medical Center and Uniformed Services of the Health Sciences, Bethesda, Maryland, USA Correspondence: Fred E.
Fred E. Yeo, Tinika A. Montgomery
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