Results 11 to 20 of about 16,655 (259)

Patient Perspectives on ADPKD

Advances in Kidney Disease and Health, 2023
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. It has been associated with a significant physical and psychological burden, leading to a reduced quality of life. The purpose of this literature review is to summarize the patient perspective on ADPKD based on the current published literature.
Gittus, M., Harris, T., Ong, A.C.M.
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Antenatally Diagnosed ADPKD [PDF]

Kidney International Reports, 2018
[Extract] Advances in antenatal ultrasonographyhave substantially improved the counseling of pregnantwomen.1 4With this advancement comes a diagnosticdilemma in the approach to antenatal diagnoses of cystickidney disease. The differential diagnosis of enlargedcystic echogenic kidneys includes autosomal dominantpolycystic kidney disease (ADPKD ...
Aldridge, Melanie, Patel, Chirag, Mallett, Andrew, Trnka, Peter   +3 more
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Radiologic and clinical bronchiectasis associated with autosomal dominant polycystic kidney disease. [PDF]

PLoS ONE, 2014
Polycystin 1 and 2, the protein abnormalities associated with autosomal dominant polycystic kidney disease (ADPKD), are also found in airway cilia and smooth muscle cells.
Teng Moua, Ladan Zand, Robert P Hartman, Thomas E Hartman, Dingxin Qin, Tobias Peikert, Qi Qian   +6 more
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Bone health in autosomal dominant polycystic kidney disease (ADPKD) patients after kidney transplantation

Bone Reports, 2023
ADPKD is caused by pathogenic variants in PKD1 or PKD2, encoding polycystin-1 and -2 proteins. Polycystins are expressed in osteoblasts and chondrocytes in animal models, and loss of function is associated with low bone mineral density (BMD) and volume ...
Dalia Zubidat, Christian Hanna, Amarjyot K. Randhawa, Byron H. Smith, Maroun Chedid, Daniel-Hasan N. Kaidbay, Luca Nardelli, Yaman G. Mkhaimer, Reem M. Neal, Charles D. Madsen, Sarah R. Senum, Adriana V. Gregory, Timothy L. Kline, Ziad M. Zoghby, Stephen M. Broski, Naim S. Issa, Peter C. Harris, Vicente E. Torres, Jad G. Sfeir, Fouad T. Chebib   +19 more
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Giant Bilateral Adrenal Myelolipoma: Case Report

Indian Journal of Endocrinology and Metabolism, 2020
Adrenal myelolipomas are nonfunctional tumors that are usually asymptomatic; however, they have been known to coexist with other endocrine disorders, such as Cushing's syndrome, congenital adrenal hyperplasia (CAH), Conn's syndrome, and pheochromocytoma.
B Rathna Roger, Arkadeep Dhali, Rakesh S Ramesh, Christopher Dsouza   +3 more
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Cardiac structural and functional findings in Persian cats with autosomal dominant polycystic kidney disease [PDF]

Ciência Rural, 2020
: Autosomal dominant polycystic kidney disease (ADPKD) has been related to left ventricular structural and functional abnormalities in human patients. The present study aimed to evaluate the cardiac structural and functional findings in Persian cats with
Juliana Mariotti Guerra, Arine Pellegrino, Alexandre Gonçalves Teixeira Daniel, Mariana Ferreira de Freitas, Natália Cavalca Cardoso, Rebecca Bastos Pessoa, Gabriel Garone de Lucca, Maria Helena Matiko Akao Larsson, Luiz Fernando Onuchic, Felisbina Luisa Queiroga, Bruno Cogliati   +10 more
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Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
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The emerging role of cellular senescence in renal diseases [PDF]

, 2020
Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco, Chen, Rong, Francis, Heather, Glaser, Shannon, Li, Siwen, Li, Xuesen, Meng, Fanyin, Wan, Ying, Wu, Nan, Zhang, Chunmei, Zhou, Bingru, Zhou, Tianhao, Zou, Ping   +12 more
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ARPKD and ADPKD [PDF]

Journal of the American Society of Nephrology, 2008
Superficially, autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) seem to be more different than alike. ADPKD is common, its cysts arise from any nephron segment, and it is slowly progressive.[1][1] Hepatic cysts are its primary ...
Jun-ya Kaimori, Gregory G. Germino
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Intrafamilial Variability of ADPKD [PDF]

Kidney International Reports, 2019
Discordance in kidney disease severity between affected relatives is a recognized feature of autosomal dominant polycystic kidney disease (ADPKD). Here, we report a systematic study of a large cohort of families to define the prevalence and clinical features of intrafamilial discordance in ADPKD.The extended Toronto Genetic Epidemiology Study of ...
Matthew B. Lanktree, Elsa Guiard, Weili Li, Pedram Akbari, Amirreza Haghighi, Ioan-Andrei Iliuta, Belili Shi, Chen Chen, Ning He, Xuewen Song, Peter J. Margetts, Alistair J. Ingram, Korosh Khalili, Andrew D. Paterson, York Pei   +14 more
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