Results 41 to 50 of about 16,655 (259)
Frontiers in Cell and Developmental Biology, 2020 Autosomal dominant polycystic kidney disease (ADPKD) is a complex process, involving the alteration of multiple genes and signaling pathways, and the pathogenesis of ADPKD remains largely unknown.
Ai-Wen Shen +8 more
doaj +1 more source
Polycystins, ADPKD, and Cardiovascular Disease
Kidney International Reports, 2020 Cardiovascular disorders are the most common cause of mortality in autosomal dominant polycystic kidney disease (ADPKD). This review considers recent clinical and basic science studies that address the contributing factors of cardiovascular dysfunction in ADPKD. In particular, attention is placed on how dysfunction of the polycystin proteins located in
Ivana Y. Kuo, Arlene B. Chapman
openaire +3 more sources
Acute Kidney Injury in ADPKD Patients with Pneumonia
International Journal of Nephrology, 2011 Background. In animal models, polycystic kidneys are susceptible to acute kidney injury (AKI). We examined the occurrence of AKI in a cohort of autosomal dominant polycystic kidney disease (ADPKD) and non-ADPKD patients with acute pneumonia. Design.
Carlos Franco Palacios +8 more
doaj +1 more source
CD133 and CD24 expression in renal tissue of patients affected by autosomal dominant polcystic kidney disease [PDF]
, 2013 Background: Autosomal dominant polycystic kidney disease is a condition mainly character- ized by the progressive development and enlar- gement of cysts in each kidney.
CAPPELLI, Gianni +5 more
core +1 more source
Canadian Journal of Kidney Health and Disease, 2017 Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disorder worldwide. The disease is characterized by renal cysts and progressive renal failure due to progressive enlargement of cysts and renal fibrosis. An estimated
Steven Soroka +9 more
doaj +1 more source
Tolvaptan in Pediatric Autosomal Dominant Polycystic Kidney Disease: From Here to Where?
Kidney Diseases, 2021 Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, accounting for approximately 5% of all ESRD cases worldwide.
Fei Liu +4 more
doaj +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2018 Bilateral ADPKD is a well-known entity, but there are only a few reports on unilateral ADPKD in adults, most of which had associated contralateral agenesis. Further rare is the development of RCC in unilateral ADPKD.
Anupama Tandon +4 more
doaj +1 more source
Surgical cyst decortication in autosomal dominant polycystic kidney disease [PDF]
, 2013 PURPOSE: To provide a summary of the relevant literature regarding the impact of surgical cyst decortication on hypertension, renal function, and pain management in patients with autosomal dominant polycystic kidney disease (ADPKD).
Bhayani, Sam B +5 more
core +2 more sources
EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease
Exploration, EarlyView.ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren +15 more
wiley +1 more source
Hypertension in autosomal dominant polycystic kidney disease: a meta-analysis [PDF]
, 2016 CONTEXT: Autosomal dominant polycystic kidney disease (ADPKD) is a common disorder that can cause hypertension during childhood, but the true prevalence of hypertension during childhood is not known.
Cuthell, O +5 more
core +1 more source