Results 11 to 20 of about 135,585 (316)

Age-related Changes in the Adrenal Cortex: Insights and Implications

open access: yesJournal of the Endocrine Society, 2023
Aging is characterized by a gradual decline in physiological function. This process affects all organs including the adrenal cortex, which normally functions to produce essential steroid hormones including mineralocorticoids, glucocorticoids, and ...
Kate M Warde   +2 more
semanticscholar   +1 more source

The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease

open access: yesInternational Journal of Molecular Sciences, 2021
Many adrenocortical diseases are more prevalent in women than in men, but the reasons underlying this sex bias are still unknown. Recent studies involving gonadectomy and sex hormone replacement experiments in mice have shed some light onto the molecular
Rodanthi Lyraki, A. Schedl
semanticscholar   +1 more source

Adrenal cortex development and maintenance; knowledge acquired from mouse models.

open access: yesEndocrinology, 2021
The adrenal cortex is an endocrine organ organized into concentric zones that are specialized to produce specific steroid hormones essential for life. The development and maintenance of the adrenal cortex are complex, as a fetal adrenal is first formed ...
Nour Abou Nader, A. Boyer
semanticscholar   +1 more source

Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis

open access: yesCase Reports in Endocrinology, 2021
Primary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones.
Ni Wayan Wina Dharmesti   +4 more
doaj   +1 more source

Late diagnosis of primary chronic adrenal insufficiency in the framework of autoimmune polyglandular syndrome type 2. Clinical observation

open access: yesЛечащий Врач, 2023
Chronic adrenal insufficiency is caused by insufficient secretion of hormones by the adrenal cortex due to dysfunction of one or more links of the hypothalamic-pituitary-adrenal system.
V. G. Chobitko, A. P. Belova
doaj   +1 more source

A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads

open access: yesFrontiers in Endocrinology, 2022
Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one of the most important precursors of sex hormones. However, the underlying biological mechanism remains largely unknown. Herein, we sequenced human fetal
Yifu Wang   +93 more
doaj   +1 more source

Imbalanced cortisol concentrations in glycogen storage disease type I: evidence for a possible link between endocrine regulation and metabolic derangement

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Glycogen storage disease type I (GSDI) is an inborn error of carbohydrate metabolism caused by mutations of either the G6PC gene (GSDIa) or the SLC37A4 gene (GSDIb).
Alessandro Rossi   +9 more
doaj   +1 more source

Measurement of the adrenal cortex reserve using depot beta 1-24-corticotrophin. II---in thyroid diseases.

open access: yesActa Médica Portuguesa, 1979
Mean plasma cortisol 4 to 6 hours after 1 mg Synacthen Depot in normal subjects, simple goiter and hypothyroidism were not significantly different. On the contrary after stimulation cortisol levels in untreated hyperthyroidism were significantly below ...
A. Galvão-Teles
doaj   +1 more source

Use of hyaluronic acid associated with triamcinolone acetonide or ozone gas in the treatment of induced osteoarthritis in rabbits

open access: yesActa Cirúrgica Brasileira, 2021
Purpose: To evaluate the effects of the intra-articular application of hyaluronic acid associated with triamcinolone acetonide, and ozone gas in the treatment of induced osteoarthritis in rabbit’s stifles.
Giovanna Cristina Brombini   +8 more
doaj   +1 more source

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