Results 31 to 40 of about 650,508 (231)

Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial.
Ji Young Hong, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung, Seung Hun Jang   +5 more
doaj   +1 more source

Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex

, 2022
The cortex of the adrenal gland is organized into concentric zones that produce distinct steroid hormones essential for body homeostasis in mammals. Mechanisms leading to the development, zonation and maintenance of the adrenal cortex are complex and ...
Gustavo Zamberlam, Zamberlam, Gustavo, Abou Nader, Nour, Nour Abou Nader, Alexandre Boyer, Boyer, Alexandre   +5 more
core   +1 more source

Angiotensin peptides in the regulation of adrenal cortical function

Exploration of Medicine, 2021
The adrenal cortex plays a key role in the regulation of metabolism, salt and water homeostasis and sex differentiation by synthesizing glucocorticoid, mineralocorticoid and androgen hormones.
Gian Paolo Rossi, Livia Lenzini, Brasilina Caroccia, Giacomo Rossitto, Teresa Maria Seccia   +4 more
doaj   +1 more source

Development of a transplantable bioartificial adrenal cortex [PDF]

, 2023
Adrenal insufficiency is a life-threatening disease, in which adrenocortical cells fail to produce adequate amount of steroid hormones, mostly glucocorticoids (cortisol) and mineralocorticoids (aldosterone).
Malyukov, Maria
core   +2 more sources

Adrenal Oncocytic Neoplasm with Paradoxical Loss of Important Mitochondrial Steroidogenic Protein: The 18 kDA Translocator Protein

Case Reports in Endocrinology, 2017
The adrenal glands produce a variety of hormones that play a key role in the regulation of blood pressure, electrolyte homeostasis, metabolism, immune system suppression, and the body’s physiologic response to stress.
Roberto Ruiz-Cordero, Alia Gupta, Arumugam R. Jayakumar, Gaetano Ciancio, Gunnlaugur Petur Nielsen, Merce Jorda   +5 more
doaj   +1 more source

Modulation of the hypothalamic-pituitary-adrenal axis of an Arctic-breeding polygynandrous songbird, the Smith's longspur, Calcarius pictus [PDF]

, 2003
To successfully reproduce in the Arctic, birds must modulate their neuroendocrine and behavioural systems. These adjustments include an attenuation of the stress responsiveness of the hypothalamic-pituitary-adrenal (HPA) axis to external stimuli and a ...
Wingfield, John C, Meddle, Simone L; id_orcid, Richardson, Matthew I, Owen-Ashley, Noah T   +3 more
core   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Adrenocortical zonation, renewal, and remodeling

Frontiers in Endocrinology, 2015
The adrenal cortex is divided into concentric zones. In humans the major cortical zones are the zona glomerulosa, zona fasciculata, and zona reticularis.
Marjut ePihlajoki, Julia eDörner, Rebecca S. Cochran, Markku eHeikinheimo, David B Wilson   +4 more
doaj   +1 more source

Multi‐Layer Transcriptomic Comparison Across Human, Pig, and Mouse Informs Tissue‐ and Trait‐Specific Animal Model Selection

Advanced Science, EarlyView.
We integrated RNA‐seq data from humans, pigs, and mice across 15 matched tissues based on 14 910 one‐to‐one orthologous genes. Cross‐species similarity was systematically evaluated across multiple regulatory layers, including global co‐expression conservation, co‐expression networks, tissue‐specific programs, and 3D genome architecture.
Jingwen Dou, Yong Liao, Xiong Shen, Xin Huang, Zhenshuang Tang, Yuwei Gou, Huajun Zhou, Jingya Xu, Hong Liu, Yue Wang, Keke Liang, Jia Liu, Xiao Zhang, Chenyao Li, Shangjian Wang, Liangliang Fu, Lilin Yin, Xinyun Li, Shuhong Zhao, Xiaolei Liu, Jingjin Li, Yuhua Fu   +21 more
wiley   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source