Results 71 to 80 of about 113,866 (372)

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman, Pablo Duarte, Esteban Dauden, Antonio Cuadrado, María Isabel Rodríguez‐Franco, Manuela G. López, Rafael León   +6 more
wiley   +1 more source

Three-dimensional Volumetric Ultrasonography of Enlarged Adrenal Gland in Dog [PDF]

Iranian Journal of Veterinary Surgery, 2011
Objective: Detection and evaluation of adrenal glands are complex problems in conventional ultrasonography in dogs. Using three-dimensional (3D) ultrasonography (US) in adrenal gland volume evaluation can add new potential for further adrenal studies ...
Shaghayegh Asadi, Mohammad Molazem, Majid Masoudifard, Shahram Jamshidi, Sarang Soroori, Noshin Ghazale   +5 more
doaj  

A Touch Enabled Hemodynamic and Metabolic Monitor

Advanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi, Tamoghna Saha, Ponnusamy Nandhakumar, Muhammad Inam Khan, Hannah Fishman, Sara Earney, Chochanon Moonla, Yuchen Xu, Henry Thai, Sofia Morales‐Fermin, Gyeongho Kim, Rhea Park, Beya Acot, Oscar Wu, Cannon Wurster, An‐Yi Chang, Christopher Cheung, Julia Silberman, Shichao Ding, Joseph Wang   +19 more
wiley   +1 more source

Compound heterozygous loss‐of‐function variants in BRAT1 cause lethal neonatal rigidity and multifocal seizure syndrome

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
Trio‐based whole‐exome sequencing (WES) and Sanger sequencing identified a novel splicing mutation c.431‐2A>G and a heterozygous truncating mutation c.1359_1361del in BRAT1 in the proband. In addition, our research demonstrated the intronic mutation could lead to aberrant mRNA splicing and further contributed to a better understanding and establishment
Shan Li, Shunan Yu, Yanzhuo Zhang, Ying Wang, Xu Jiang, Chengai Wu   +5 more
wiley   +1 more source

The morphology of the adrenal gland in the European bison (Bison bonasus) [PDF]

, 2016
BACKGROUND: The anatomy of the adrenal glands has been widely studied in many species of domestic and wild mammals. However, there are no available literature reports describing the morphology and morphometry of the adrenal glands of the European bison ...
Helena Przespolewska, Joanna Klećkowska-Nawrot, Karolina Barszcz, Karolina Goździewska-Harłajczuk, Katarzyna Olbrych, Marta Kupczyńska, Michał Czopowicz   +6 more
core   +1 more source

A Pathologist-Informed Workflow for Classification of Prostate Glands in Histopathology [PDF]

First International Workshop, MOVI 2022, Held in Conjunction with MICCAI 2022, Singapore, September 18, 2022, Proceedings, https://link.springer.com/book/10.1007/978-3-031-16961-8, 2022
Pathologists diagnose and grade prostate cancer by examining tissue from needle biopsies on glass slides. The cancer's severity and risk of metastasis are determined by the Gleason grade, a score based on the organization and morphology of prostate cancer glands.
arxiv  

Acoustic radiation force impulse (ARFI) elastography of adrenal glands in healthy adult dogs

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
To describe the ARFI elastography in the evaluation of the adrenal glands in adult dogs, to evaluate the stiffness of adrenal parenchyma and to determine the qualitative and quantitative standards of the ARFI technique, which have not yet been described ...
S. Fernandez, M.A.R. Feliciano, S. Borin-Crivellenti, L.Z. Crivellenti, M.C. Maronezi, A.P.R. Simões, P.D.A. Silva, R.R. Uscategui, N.R.N. Cruz, A.E. Santana, W.R.R. Vicente   +10 more
doaj   +1 more source

Primary hyperaldosteronism: challenges in subtype classification

BMC Research Notes, 2012
Background Primary hyperaldosteronism (PA) is a serious and potentially debilitating disease. Detailed guidelines have been written to guide endocrinologists in establishing the diagnosis of PA as well as in subtype classification of PA. The objective of
Layden Brian T, Hahr Allison J, Elaraj Dina M   +2 more
doaj   +1 more source

Current Approach for Diagnosis and Treatment of Adrenal Tuberculosis—Our Experience and Review of Literature

The Surgery Journal, 2022
Addison's disease was first described by Thomas Addison in 1855. He demonstrated the destruction of bilateral adrenal gland by tuberculosis (TB) in six patients.
Stuti Gupta, Md Abu Masud Ansari, Arun Kumar Gupta, Poras Chaudhary, Lalit Kumar Bansal   +4 more
doaj   +1 more source