Results 71 to 80 of about 70,943 (332)

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

A Case of primary adrenal lymphoma presenting with adrenal insufficiency

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2018
Non-Hodgkin lymphoma (NHL) with secondary involvement of the adrenal gland is not uncommon, however primary adrenal lymphoma leading to adrenal insufficiency is a rare occurrence.
G.P. Samarasinghe, C.N. Antonypillai, U.P. Kalubowila, R.M.P. Ratnayake, E.M.S.B. Ekanayake, B.M.I.K. Thilakarathne   +5 more
doaj   +1 more source

A rare occurrence of central precocious puberty in adrenal hypoplasia congenita

Sri Lanka Journal of Medicine, 2020
AHC (X-linked adrenal hypoplasia congenita) is a rare cause of adrenal insufficiency due to mutations in the DAX1 gene. It traditionally causes hypogonadotropic hypogonadism.
Rajesh Joshi, Karthik Shroff
doaj   +1 more source

Pre-hospital management of acute Addison’s Disease – Audit of patients attending a referral hospital in a regional area [PDF]

, 2019
Context: Adrenal crises (AC) cause morbidity and mortality in patients with Addison’s disease [primary adrenal insufficiency (PAI)]. Patient-initiated oral stress dosing, with parenteral hydrocortisone, is recommended to avert ACs. While these should be
Goubar, Thomas, McGrath, Shaun, Rushworth, R Louise, Torpy, David J   +3 more
core   +1 more source

Reported adverse drug reactions during the use of inhaled steroids in children with asthma in the Netherlands [PDF]

, 2006
Objective: Inhaled corticosteroids (ICS) are widely used in the treatment of asthma. We studied the suspected adverse drug reactions (sADRs) reported during the use of ICS in the Netherlands. Methods: In the Netherlands, health professionals and patients
de Jong-van den Berg, L.T.W., de Vries, T.W., Duiverman, E.J., Langen-Wouterse, J.J., van Puijenbroek, E.   +4 more
core   +1 more source

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk, Neslihan Balci, Osman Nuri Aslan, Erbay Kalay   +3 more
wiley   +1 more source

Current Approach for Diagnosis and Treatment of Adrenal Tuberculosis—Our Experience and Review of Literature

The Surgery Journal, 2022
Addison's disease was first described by Thomas Addison in 1855. He demonstrated the destruction of bilateral adrenal gland by tuberculosis (TB) in six patients.
Stuti Gupta, Md Abu Masud Ansari, Arun Kumar Gupta, Poras Chaudhary, Lalit Kumar Bansal   +4 more
doaj   +1 more source

Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource Limited Setting in Tanzania: A Case Report, Clinical Discussion and Brief Review of Existing Literature. [PDF]

, 2012
Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor ...
A Cénac, A Gutenberg, A Lecube, AH Zargar, C Ajith, D Castle, EH Sidibe, EM Tan, F Bakiri, Faheem G Sheriff, GK Leung, H Raff, HC Lee, J Honegger, JD Ji, JR Ouma, Kajiru G Kilonzo, ME Molitch, N Tubridy, P Caturegli, R Golden, R Goswami, RA Kristof, S Diederich, William P Howlett, Y Ozawa, Z Karaca, ZA Erkut   +27 more
core   +3 more sources

Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study

British Journal of Clinical Pharmacology, EarlyView.
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers, Letao Li, Anna C. M. Kluivers, Michelle Broekhuizen, Madhavi S. Harhangi, A. H. Jan Danser, Irwin Reiss, Karel Allegaert, Sjoerd A. A. van den Berg, Bertrand D. van Zelst, Ron H. N. van Schaik, Philip L. J. DeKoninck, Emma Ronde, Sebastiaan D. T. Sassen, Sinno H. P. Simons, Birgit C. P. Koch   +15 more
wiley   +1 more source

Preclinical Cushing's syndrome in adrenal incidentalomas [PDF]

, 1992
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally discovered adrenal tumors.
Allolio, B., Krestin, G. P., Nieke, J., Reincke, Martin, Saeger, W., Winkelmann, W.   +5 more
core