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Archives of Disease in Childhood, 2011
Premature adrenarche refers to the presence of secondary sexual hair in girls younger than 8 years old and boys younger than 9 years old. It is a relatively common presentation to paediatricians and is more frequent in girls than boys. It is a benign diagnosis, but other causes of androgen excess such as congenital adrenal hyperplasia or adrenal ...
Rachel M, Williams +2 more
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Premature adrenarche refers to the presence of secondary sexual hair in girls younger than 8 years old and boys younger than 9 years old. It is a relatively common presentation to paediatricians and is more frequent in girls than boys. It is a benign diagnosis, but other causes of androgen excess such as congenital adrenal hyperplasia or adrenal ...
Rachel M, Williams +2 more
openaire +2 more sources
Journal of Pediatric Health Care, 2008
Premature adrenarche refers to the precocious secretion of adrenal androgens, which results in the isolated development of pubic hair (pubarche) before the age of eight years in girls and nine years in boys. The female to male ratio is approximately 10:1.
Alexander K C, Leung, Wm Lane M, Robson
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Premature adrenarche refers to the precocious secretion of adrenal androgens, which results in the isolated development of pubic hair (pubarche) before the age of eight years in girls and nine years in boys. The female to male ratio is approximately 10:1.
Alexander K C, Leung, Wm Lane M, Robson
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‘Exaggerated adrenarche’ in children presenting with premature adrenarche
Clinical Endocrinology, 1995SummaryOBJECTIVE Previous reports of endocrinological profiles in children presenting with premature adrenarche have not shown consistent abnormalities. We therefore aimed to review the clinical and biochemical aspects of a large number of patients presenting with premature adrenarche without virilization and determine the relation between clinical and
S, Likitmaskul +6 more
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Adrenal changes associated with adrenarche [PDF]
Reviews in Endocrine and Metabolic Disorders, 2008 The mechanisms causing the rise in adrenal androgen production during the course of adrenarche remain to be defined. However, the increase in steroid release is clearly associated with a series of intra-adrenal changes in the expression of steroidogenic enzymes needed for dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS ...
William Rainey, Takashi Suzuki
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Associations between early adrenarche, affective brain function and mental health in children
Social Cognitive and Affective Neuroscience, 2015 Early timing of adrenarche, associated with relatively high levels of Dehydroepiandrosterone (DHEA) in children, has been associated with mental health and behavioral problems.
George C. Patton +2 more
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Endocrinology and Metabolism Clinics of North America, 1991
Between 6 and 8 years of age, while cortisol concentrations and production rates remain constant, urinary excretion and circulating concentrations of DHA, DHAS, and other adrenal androgens increase progressively. These hormonal changes, which constitute the adrenarche, are accompanied by the appearance of axillary and pubic hair and a transient ...
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Between 6 and 8 years of age, while cortisol concentrations and production rates remain constant, urinary excretion and circulating concentrations of DHA, DHAS, and other adrenal androgens increase progressively. These hormonal changes, which constitute the adrenarche, are accompanied by the appearance of axillary and pubic hair and a transient ...
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Clinical Pediatrics, 1986
Premature adrenarche (PA) or isolated growth of sexual hair in young children, is a benign condition that may initially be confused with true precocious puberty or pathologic virilizing disorders. The clinical findings, family history, and serum concentrations of dehydroepiandrosterone sulfate (DHEA-S) were compared in 24 children with PA (79% black ...
P B, Kaplowitz +2 more
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Premature adrenarche (PA) or isolated growth of sexual hair in young children, is a benign condition that may initially be confused with true precocious puberty or pathologic virilizing disorders. The clinical findings, family history, and serum concentrations of dehydroepiandrosterone sulfate (DHEA-S) were compared in 24 children with PA (79% black ...
P B, Kaplowitz +2 more
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Early Adiposity Rebound and Premature Adrenarche
Journal of Pediatrics, 2017 To examine differences in the growth pattern and the age at adiposity rebound (AR) between children with premature adrenarche (PA) and their healthy peers (controls).In this cross-sectional study of 82 prepubertal children with PA and 63 controls, the main outcome measures were height and body mass index SDS progression, from birth to presentation at ...
Georgios P. Chrousos +2 more
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Adrenarche in comparative perspective
American Journal of Human Biology, 2010AbstractObjectives: To addresses the hypothesis that human adrenarche is associated with extended juvenile brain development by comparing the timing of adrenal androgen production, brain development and lactation in a larger comparative mammalian context.Methods: Findings from published literature are used to compare the developmental timing of adrenal
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Adrenarche and Middle Childhood
Human Nature, 2011Middle childhood, the period from 6 to 12 years of age, is defined socially by increasing autonomy and emotional regulation, somatically by the development of anatomical structures for subsistence, and endocrinologically by adrenarche, the adrenal production of dehydroepiandrosterone (DHEA).
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