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Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study

Human Brain Mapping, Volume 47, Issue 2, February 1, 2026.
A multimodal analysis with cross‐validation was employed to examine the associations between pubertal hormones (oestradiol, testosterone, and dehydroepiandrosterone) and brain structure and function in early adolescent females. The findings indicate both unique and overlapping neural correlates of these hormones.
Muskan Khetan +6 more
wiley +1 more source

Accelerated Early Childhood Growth Is Associated With the Development of Earlier Adrenarche and Puberty. [PDF]

CONTEXT Small birth size and increased postnatal growth have been associated with earlier timing of adrenarche and puberty, but it is not well known whether these factors alone or together lead to earlier maturation. OBJECTIVE This work aimed to
Lakka, Timo A +7 more
core +2 more sources

Pubertal hormones predict sex-specific trajectories of pituitary gland volume during the transition from childhood to adolescence

NeuroImage, 2020
Pituitary gland volume (PGV) increases during childhood and adolescence in a sex-specific manner, and previous research suggests that puberty may be associated with PGV development.
Sarah Whittle +4 more
doaj +1 more source

PREMATURE ADRENARCHE IN IDENTICAL TWINS

Acta Paediatrica, 1976
Abstract. Monozygotic female twins with premature adrenarche are reported. Endocrine work‐up excluded the existence of an endocrinopathy or a tumor.
BARTSOCAS, CS, DANON, M, CRAWFORD, JD
openaire +3 more sources

Linear Growth in Children With Cystic Fibrosis in the Netherlands Born Between 1997–2004; Results of a Multicenter Cohort Analysis

Pediatric Pulmonology, Volume 61, Issue 2, February 2026.
ABSTRACT Objectives Short stature has been associated with reduced life expectancy in people with Cystic Fibrosis (pwCF). We aimed to evaluate linear growth and final height in a Dutch cohort of children with CF, diagnosed in early childhood and now aged ≥ 18 years and identify risk factors for impaired linear growth. Methods A multicenter longitudinal
Tamer G. +8 more
wiley +1 more source

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL‐Related Disorders: A Cross‐Sectional Caregiver Survey Analysis

American Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 35-58, January 2026.
ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring +4 more
wiley +1 more source

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

American Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 205-214, January 2026.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart +336 more
wiley +1 more source

Premature adrenarche

, 2021
Pubertet je životno razdoblje na prijelazu iz djetinjstva u odraslu dob. Glavne su karakteristike puberteta pojava sekundarnih spolnih oznaka, ubrzani tjelesni rast i razvoj te postizanje spolne i reprodukcijske zrelosti.
Mesić, Adrijana
core

Research Review: On the (mis)use of puberty data in the ABCD Study® – a systematic review, problem illustration, and path forward

Journal of Child Psychology and Psychiatry, Volume 67, Issue 1, Page 138-151, January 2026.
Background The Adolescent Brain Cognitive DevelopmentSM (ABCD) Study® has significant potential to reveal the nature, causes, context, and consequences of pubertal development in diverse American youth. Optimal use of the data requires thoughtful consideration of puberty: how it is likely to affect psychological and neural development, and its ...
Adriene M. Beltz +8 more
wiley +1 more source

Puberty in girls with Prader-Willi syndrome: cohort evaluation and clinical recommendations in a Latin American tertiary center

Frontiers in Endocrinology
IntroductionPrader-Willi syndrome (PWS) is a genetic disorder characterized by hypothalamic-pituitary deficiencies including hypogonadism. In girls with PWS, hypogonadism can present early in childhood, leading to genital hypoplasia, delayed puberty ...
Caroline Gouveia Buff Passone +10 more
doaj +1 more source

premature adrenarche
puberty
dheas

dhea
precocious puberty
dehydroepiandrosterone sulfate

prader-willi syndrome
pubarche