Results 51 to 60 of about 3,006 (196)

Adrenarcheal hormone-related development of white matter during late childhood

NeuroImage, 2020
The aim of the current study was to longitudinally examine how adrenarcheal hormones influence the development of white matter structure from age 8.5 to 10 years.
Marjolein E.A. Barendse, Julian G. Simmons, Robert E. Smith, Marc L. Seal, Sarah Whittle   +4 more
doaj   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, Volume 14, Issue 5, Page 1172-1182, July 2026.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Adrenarche in Prader-Willi syndrome appears not related to insulin sensitivity and serum adiponectin [PDF]

, 2007
Prader-Willi syndrome (PWS) is a genetic disorder characterized by dysmorphic features, obesity, hypogonadism, hypotonia and mental retardation. Obesity has been linked to insulin resistance and the latter has also been associated with premature ...
Bazaes, Rodrigo, Mericq, Verónica, Unanue, Nancy, Iñíguez Vila, Germán, Cortés, Fanny, Ávila, Alejandra   +5 more
core   +1 more source

Spectrum of Hypogonadism and Its Management in Adolescents With Prader‐Willi Syndrome: A Retrospective Cohort Study Over 35 Years

Clinical Endocrinology, Volume 105, Issue 1, Page 51-59, July 2026.
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen, Geoffrey Ambler, Yoon Hi Cho   +2 more
wiley   +1 more source

Endocrine Events Involved in Puberty: A Revisit to Existing Knowledge

Life and Science, 2020
Puberty is a multifaceted complex phenomenon, comprised of a series of events, controlled by hormones and other regulatory factors. It is the transition period between childhood and adolescence with key important changes occurring in physical, biological,
Shaista Aslam
doaj   +1 more source

Adrenal Biomarkers of Stress in Transgender and Gender‐Diverse Adolescents

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Transgender and gender diverse (TGD) adolescents are frequently exposed to minority stress, which may influence the hypothalamic–pituitary–adrenal (HPA) axis during critical developmental windows. Altered cortisol dynamics have been described in populations facing chronic stress, yet evidence in TGD youth is limited.
Simone Coslovich, Stefania Tonetto, Giulia Bragato, Gianluca Tamaro, Alice Fachin, Paolo Dalena, Lorenzo Zandonà, Antonella Fabretto, Egidio Barbi, Gianluca Tornese   +9 more
wiley   +1 more source

Differences in Endocrine Parameters and Psychopathology in Girls with Premature Adrenarche versus On-time Adrenarche [PDF]

Journal of Pediatric Endocrinology and Metabolism, 2008
Girls with premature adrenarche (PA) are at risk for multiple problems related to exaggerated androgen synthesis. Whether PA carries a risk of psychopathology remains unknown. This study examined group differences in: (a) anthropometric and endocrine parameters, and (b) mood and behavior problems, in 6-8 year-old girls with PA (n = 40) compared to on ...
Lorah D, Dorn, Susan R, Rose, Deborah, Rotenstein, Elizabeth J, Susman, Bin, Huang, Tammy L, Loucks, Sarah L, Berga   +6 more
openaire   +2 more sources

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, Volume 13, Issue 22, 17 April 2026.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

ADRENARCHE DURING THE GREAT RECESSION AS AN ENVIRONMENTAL CHALLENGE TO PSYCHOSOCIAL DEVELOPMENT: AN EVOLUTIONARY-DEVELOPMENTAL PERSPECTIVE [PDF]

, 2018
Adrenarche is an important developmental period to consider in relation to both physical and psychosocial outcomes. The reorganization of the stress response system during adrenarche, understood as physiological adjustment to environments that may vary ...
Nehler, Chelsea
core   +1 more source

Prevalence and severity of pre‐pubertal acne: A cohort study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Bruno Halioua, Charles Taieb, Caroline Philippe, Mohammed Bennani, Jean Daniel Daumont, Yaron Ben Hayoun, Sophie Séité, Guenaëlle Le Dantec, Margot Broallier, Caroline Le Floc'h, Ann‐Laure Demessant‐Flavigny, Delphine Kerob   +11 more
wiley   +1 more source