Results 31 to 40 of about 3,006 (196)
Adrenarche and Fetal Growth [PDF]
Dehydroepiandrosterone sulfate (DHEAS) is prenatally secreted by the fetal adrenal, is an indicator of adrenarche from late childhood onward and is a marker of the individual hormonal milieu in the adult. The regulation of DHEAS secretion is still poorly understood.
I, Francois, F, de Zegher
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The steroid metabolome of adrenarche [PDF]
Adrenarche is an endocrine developmental process whereby humans and select nonhuman primates increase adrenal output of a series of steroids, especially DHEA and DHEAS. The timing of adrenarche varies among primates, but in humans serum levels of DHEAS are seen to increase at around 6 years of age.
Juilee, Rege, William E, Rainey
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Molecular and Environmental Mechanisms Regulating Puberty Initiation: An Integrated Approach
The mechanisms underlying the initiation of puberty, one of the cornerstones of human evolution, have not been fully elucidated as yet. However, recently, an accumulating body of evidence has helped unravel several critical aspects of the process.
Sarantis Livadas, George P. Chrousos
doaj +1 more source
DHEAS and Human Development: An Evolutionary Perspective
Adrenarche, the post-natal rise of DHEA and DHEAS, is unique to humans and the African Apes. Recent findings have linked DHEA in humans to the development of the left dorsolateral prefrontal cortex (LDPFC) between the ages of 4–8 years and the right ...
Benjamin Campbell
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In healthy adolescents, delayed pubarche is generally a benign condition that is caused by a physiological discrepancy between gonadarche and adrenarche.
Francesco Baldo +2 more
doaj +1 more source
SUN-073 Urine Steroid Profile of Girls with Premature Adrenarche
Background: Adrenarche describes the development of the human adrenal cortex when the zona reticularis increases the synthesis of C19 steroids (DHEA/-S).
Sommer, Grit +3 more
core +1 more source
Interpretation of androgen and anti-Mullerian hormone profiles in a Hispanic cohort of 5- to 8-year-old girls with premature adrenarche [PDF]
Purpose Premature adrenarche (PA) often leads to polycystic ovary syndrome (PCOS). Higher anti-mullerian hormone (AMH) levels are reported in PCOS. We studied the androgen profile and AMH profiles in Hispanic girls with PA (aged 5–8 years) and age and ...
Preneet Cheema Brar +5 more
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Familial Hyperinsulinism due to HNF4A Deficiency and Benign Premature Adrenarche: A Case Report
Background: Familial Hyperinsulinism due to HNF4A deficiency (FHI-HNF4A) is a form of diazoxide-sensitive, diffuse hyperinsulinism, characterized by transient or persistent hyperinsulinemic hypoglycemia, and a propensity to develop Maturity-Onset ...
Edward Compton +2 more
doaj +1 more source
Background: Dehydroepiandrosterone sulphate (DHEAS), the most plentiful circulating adrenal hormone, may be considered as a marker of the onset of adrenarche and is involved in pubertal development and metabolic disorders.
Hongjuan Li +3 more
doaj +1 more source
Delayed adrenache in thalassaemia: a case series
Thalassemia major is a transfusion dependent genetically inherited haematological disorder that could lead to multiple endocrinopathies due to the chronic hypoxia and iron over load that is associated with this condition.
W. K. M. G. Amarawardhena +1 more
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