Results 11 to 20 of about 3,006 (196)
Adrenarche as a regulator of sensitivity to early adversity. [PDF]
J NeuroendocrinolAbstract The human brain is highly sensitive to early adversity, which can have long‐term consequences for later mental health. It is also a time of rapid learning of social, motor and other skills, including language. It is proposed that pre‐adrenarche, the only epoch in human development in which cortisol is not accompanied by dehydroepiandrosterone (
Herbert J.
europepmc +5 more sources
Pediatric Annals, 2018 Adrenarche is when a child's adrenal cortex starts to secrete adrenal androgen precursors. Dehydroepiandrosterone (DHEA) is the most abundant product of the adrenal cortex, and is a weak androgen agonist thought to be responsible for the clinical signs of pubarche by conversion to more potent androgens, testosterone, and ...
Laura, Novello, Phyllis W, Speiser
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The timing of adrenarche in Maya girls, Merida, Mexico [PDF]
, 2020 In this pilot study we investigated age at adrenarche and body composition among 25 urban Maya girls aged 7-9 living in low-income, urban households in Merida, Mexico.
Federico Dickinson (680946) +9 more
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Adrenarche and pubarche in girls with turner syndrome during growth-promoting therapy with human growth hormone [PDF]
BMC Endocrine Disorders, 2019 Background Data on adrenarche and pubarche in girls with Turner syndrome (TS) are inconsistent in the literature. Methods The cohort consisted of 94 girls and young women with TS born between 1971 and 2001 (age range: 3.1–23.2 yrs.), who were treated ...
Helmuth G. Dörr +5 more
doaj +2 more sources
BMC GenomicsBackground Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common cause of chronic liver disease in children and adolescents, but its etiology remains largely unknown.
Haoqing Li +4 more
doaj +2 more sources
Characteristics of growth in children with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency during adrenarche and beyond. [PDF]
, 2022 CONTEXT Patients with classic congenital adrenal hyperplasia (CAH) often fail to achieve their full growth potential. Adrenarche may accelerate bone maturation and thereby result in decreased growth in CAH.
Flück, Christa E. +6 more
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Premature Adrenarche in Girls Characterized By Enhanced 17,20-Lyase and 17β-Hydroxysteroid Dehydrogenase Activities [PDF]
, 2020 Context: Girls with premature adrenarche (PA) may have a higher risk of developing polycystic ovary syndrome (PCOS) and metabolic syndrome. The biological purpose of adrenarche is unknown and the role of novel biosynthetic pathways remains unclear ...
Flück, Christa E. +3 more
core +3 more sources
Predicted Adult Height Remained Normal in Children With Premature Adrenarche Despite Advanced Bone Age. [PDF]
Acta PaediatrABSTRACT Aim Aetiological factors affecting the phenotype of adrenarche are largely unknown. This study investigated the phenotypic variability of premature adrenarche. Methods In this cross‐sectional retrospective registry study, data on 91 mainly Caucasian children diagnosed with premature adrenarche were retrieved from patient records.
Kanniainen E +2 more
europepmc +2 more sources
Frontiers in Endocrinology, 2023 Prader–Willi syndrome (PWS) is a rare genetic disorder resulting from lack of expression of the paternally derived chromosome 15q11–13, associated with several complications, including pubertal disorders, short stature, hyperphagia, obesity, glucose ...
Alessia Aureli +5 more
doaj +1 more source
Frontiers in Endocrinology, 2022 ContextWiedemann-Steiner Syndrome (WSS) is a genetic disorder associated with an array of clinical phenotypes, including advanced bone age and short stature.
Katherine Buchanan +4 more
doaj +1 more source