Results 71 to 80 of about 42,588 (295)

The Effect of Dexmedetomidine on the Acute Pain After Cardiothoracic Surgeries: A Systematic Review

open access: yesBrazilian Journal of Cardiovascular Surgery
Introduction: Acute post-operative pain remains a troublesome complication of cardiothoracic surgeries. Several randomized controlled trials have examined the efficacy of dexmedetomidine as a single or as an adjuvant agent before, during and after ...
Valiollah Habibi   +2 more
doaj   +1 more source

Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

open access: yesHealth Technology Assessment, 2016
Background: Care of critically ill patients in intensive care units (ICUs) often requires potentially invasive or uncomfortable procedures, such as mechanical ventilation (MV). Sedation can alleviate pain and discomfort, provide protection from stressful
Moira Cruickshank   +7 more
doaj   +1 more source

Phenotyping Overactive Bladder—Part 1: Are There Different Types of Urgency and Can They be Translated to Clinical, Urodynamic and Radiological Phenotyping? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Overactive bladder (OAB) is defined as urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urgency urinary incontinence (OAB‐wet) or without (OAB‐dry), in the absence of urinary tract infection or other detectable disease.
John E. Speich   +9 more
wiley   +1 more source

Alpha-adrenergic receptor agonists in terms of modern views on glaucoma monitoring and treatment [PDF]

open access: yesКлиническая офтальмология, 2019
The article reviews historical aspects of direct and indirect (by reducing intraocular pressure (IOP)) neuroprotective effect of brimonidine in terms of modern views on glaucoma monitoring and treatment.
V.P. Erichev   +5 more
doaj  

Facilitation of spatial working memory performance following intra-prefrontal cortical administration of the adrenergic alpha1 agonist phenylephrine. [PDF]

open access: yes, 2015
RATIONALE: Spatial working memory is dependent on the appropriate functioning of the prefrontal cortex (PFC). PFC activity can be modulated by noradrenaline (NA) released by afferent projections from the locus coeruleus.
Bussey, TJ   +6 more
core   +4 more sources

Bladder Function and Safety of Vibegron in Men With Overactive Bladder Receiving Treatment for Benign Prostatic Hyperplasia: Outcomes From the Phase 3 Randomized Controlled COURAGE Trial

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Purpose Vibegron was associated with improvements in efficacy versus placebo and was well tolerated in men with overactive bladder (OAB) on pharmacotherapy for benign prostatic hyperplasia (BPH) in the COURAGE trial (NCT03902080). Additional safety, bladder function, and urodynamics data are provided.
Eric S. Rovner   +6 more
wiley   +1 more source

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

open access: yes, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli   +291 more
core   +2 more sources

Effect of ‘combing’ on intramuscular sedation in pigs in a clinical setting—A randomised trial

open access: yesVeterinary Record, EarlyView.
Abstract Background Pigs pose distinct challenges to the anaesthetist due to their temperament, the limitations of manual restraint and species‐specific anatomical features. Despite the importance of minimising stress during clinical procedures, gentle handling techniques tailored for pigs in a clinical setting have yet to be clearly described or ...
Kaitlynn C. Ban   +5 more
wiley   +1 more source

Dexmedetomidine as an Adjuvant in Peripheral Nerve Block

open access: yesDrug Design, Development and Therapy, 2023
Zheping Chen, Zhenzhen Liu, Chang Feng, Yanwu Jin, Xin Zhao Department of Anesthesiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, People’s Republic of ChinaCorrespondence: Yanwu Jin; Xin Zhao, Email ...
Chen Z, Liu Z, Feng C, Jin Y, Zhao X
doaj  

L-Tetrahydropalamatine: A Potential New Medication for the Treatment of Cocaine Addiction [PDF]

open access: yes, 2012
Levo-tetrahydropalmatine (l-THP) is an active constituent of herbal preparations containing plant species of the genera Stephania and Corydalis and has been approved and used in China for a number of clinical indications under the drug name Rotundine ...
Mantsch, John R., Wang​, Jia Bei
core   +1 more source

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