Results 91 to 100 of about 20,695 (270)

Prophylactic interventions to prevent rebound pain after peripheral nerve block in adults: a systematic review and network meta‐analysis of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction Rebound pain after peripheral nerve block is recognised increasingly as a postoperative complication that may diminish the benefits of regional anaesthesia. We undertook a systematic review and network meta‐analysis to evaluate pharmacological strategies for its prevention.
Narinder Pal Singh, Jeetinder Kaur Makkar, Chelsea Zhang, Anuradha Borle, Preet Mohinder Singh   +4 more
wiley   +1 more source

Topical administration of adrenergic receptor pharmaceutics and nerve growth factor

, 2010
Jena J SteinleDepartments of Ophthalmology and Anatomy and Neurobiology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USAAbstract: Topical application of nerve growth factor (NGF) and adrenergic receptor ...
Jena J Steinle
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Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan, Celine Lee, Kaweh Daniel Zohalinejad, Mads Odgaard Mæng, Nanna Würtz Fabrin, Sigurrós Jónsdóttir, Anne Kjærsgaard Hassing, Søren Kveiborg Yde, Charles C. Wykoff, Henrik Vorum, Yousif Subhi, Marie Ørskov, Lasse Jørgensen Cehofski   +12 more
wiley   +1 more source

Alpha2 agonists for sedation to produce better outcomes for adults with critical illness: a synopsis of the A2B RCT with cost-effectiveness and process evaluation

Health Technology Assessment
Parts of this abstract have been reproduced with permission from Walsh TS, Parker RA, Aitken LM, McKenzie CA, Emerson L, Boyd J, et al.; A2B Trial Investigators.
Timothy S Walsh, Richard A Parker, Leanne M Aitken, Lydia Emerson, Cathrine A McKenzie, Julia Boyd, Alix MacDonald, Gayle Beveridge, Annabel Giddings, David Hope, Sîan Irvine, Sharon Tuck, Nazir I Lone, Kalliopi Kydonaki, John Norrie, Benedict Creagh-Brown, Daniel F McAuley, Paul Dark, Matt P Wise, Anthony C Gordon, Gavin D Perkins, Michael C Reade, Bronagh Blackwood, Alasdair MacLullich, Robert Glen, Valerie J Page, Stephen Morris, Christopher J Weir,   +28 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Protective Effects of Dexmedetomidine and Amifostine Against Radiotherapy-Induced Kidney Injury

Life
Backgrounds: Approximately 18 million individuals were diagnosed with cancer in 2018. The rate is predicted to exceed 22 million by 2030. Radiotherapy is an essential part of cancer therapy, with well documented local and systemic side effects, including
Sule Batcik, Levent Tumkaya, Eyup Dil, Leyla Kazancioglu, Elif Gaygusuz, Zihni Acar Yazici, Zulkar Ozden, Kagan Kilinc, Tolga Mercantepe   +8 more
doaj   +1 more source

Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an alpha-1 adrenoceptor agonist

, 2011
Iontophoresis of aradrenoceptor agonists in the human forearm evoke axon reflex vasodilatation, possibly due to an accumulation of inflammatory agents at the site of iontophoresis.
Drummond, P.D.
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Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

The Effect of Dopaminergic Medication on Impulse Control and Compulsive Behaviour: A Translational Perspective. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Dopaminergic medication used in disorders like Parkinson's disease (PD) and restless legs syndrome can cause impulsive‐compulsive behaviour (ICB), often with strong negative effects on patients' quality of life. This narrative review presents translational evidence on iatrogenic ICB, taking findings from epidemiological, clinical, neuroimaging
Wolfschlag M, Espa E, Hauer KO, Timpka J, Smith R, Odin P, Cenci MA, Håkansson A.   +7 more
europepmc   +2 more sources

A expressão da proteína Fos após injeção intracerebroventricular de adrenalina em ratos saciados [PDF]

, 2014
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014Estudos prévios em nosso laboratório sugerem que a injeção de adrenalina (AD) no núcleo mediano
Flores, Rafael Appel
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