Results 111 to 120 of about 20,601 (250)

Inhibiting muscle degeneration in rotator cuff tears: integrative biologic approaches targeting regeneration, fibrosis, and metabolism. [PDF]

Stem Cells Transl Med
Chung SW, Yoon JP, Park SJ.
europepmc   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Comparative anatomy and metabolic profiles of brown and white adipose tissue in humans. [PDF]

Front Endocrinol (Lausanne)
Villarreal J, Baranova A.
europepmc   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan, Arnav Kalra, Nitin Kapoor, Deep Dutta, Kunal Mahajan, Robin Maskey, Syed Abbas Raza   +6 more
wiley   +1 more source

Advances in the Association Between the <i>ADRB2</i> Gene and Bronchial Asthma: Genetic Polymorphisms, Epigenetic Regulation, and Clinical Applications. [PDF]

Curr Issues Mol Biol
Sun X, Li Y, Bao Y.
europepmc   +1 more source

Individual and Combined Cardioprotective Effects of 1,25(OH)2D3 and Dimethyl Fumarate in an Isoproterenol‐Induced Myocardial Injury Model

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
1,25(OH)2D3 and dimethyl fumarate, administered alone or in combination, provide significant cardioprotection against isoproterenol‐induced myocardial injury by reducing oxidative stress, inflammation, and structural damage through modulation of the Nrf2/NF‐κB signaling pathways and the renin–angiotensin system (RAS).
Fatma Hande Karpuzoğlu, Serhat Kilinç, İlayda Sözmen, İlknur Bingül, Abdurrahman Fatih Aydin, Aysel Bayram, Semen Önder, Efe Akçe, Semra Doğru‐Abbasoğlu, Müjdat Uysal   +9 more
wiley   +1 more source

An Explorative Approach to Examining the Role of Ischemia and Inflammation on the Function of Autoantibodies Against G Protein-Coupled Receptors and Their Corresponding Agonists. [PDF]

Int J Mol Sci
Wallukat G, Lakatos P, Steinhorst K, Flecks M, Hohberger B.   +4 more
europepmc   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Mirabegron administration for the prevention of ureteral injuries during ureteral access sheath insertion. [PDF]

World J Urol
Ermiş O, Sabuncu K, Kaçtan Ç, Karakuş B, Sürmeli B, Boz MY, Horuz R.   +6 more
europepmc   +1 more source