Results 111 to 120 of about 20,695 (270)

Controlled Resistant Hypertension Following A Successful Renal Artery Stenting: A Rare Case Report in A Developing Country

Majalah Kardiologi Indonesia
Background Renal artery stenosis is among the etiologies of secondary hypertension in which the diagnosis and therapy are difficult. We report a case of a patient with uncontrollable hypertension with frequent episodes of malignant hypertension ...
Fatihatul Firdaus Munita, Badai Bhatara Tiksnadi, Januar Wibawa Martha, Margareta Ginanti Ratna   +3 more
doaj   +1 more source

LB787 CLE-400: A potent alpha-2 adrenergic receptor agonist for the treatment of chronic itch [PDF]

Journal of Investigative Dermatology, 2021
J. Schumann, E. Caspi, O. Goren, E. Kagan   +3 more
openaire   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

The Impact of Sex on the Median Effective Dose of Dexmedetomidine for Preoperative Sedation in Adults Undergoing Upper Limb Surgery: An Up-and-Down Sequential Allocation Study

Drug Design, Development and Therapy
Gaofei Fan, Mingming Han, Shudong Wang, Min Zhang, Fang Kang, Juan Li Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s ...
Fan G, Han M, Wang S, Zhang M, Kang F, Li J   +5 more
doaj  

Testing for Non‐Severe Heritable Platelet Function Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley, Naomi Cornish, Maria Molina Carretero, Sarah K. Westbury   +3 more
wiley   +1 more source

Comparative evaluation of intrathecal dexmedetomidine and fentanyl in patients undergoing lower-limb surgery under spinal anesthesia

Asian Journal of Medical Sciences
Background: Different adjuvants have been studied to enhance the quality and extend the duration of spinal anesthesia. The use of dexmedetomidine has been increased in recent times due to its analgesic and sedative properties.
Gurcharan Singh, Amit Kumar , Pulkit Sharma , Nidhi Kumari , Neha Sinha , Muskan   +5 more
doaj   +1 more source

Pharmacological and Molecular Characterisation of P2Y Receptors in Endothelial and Epithelial Cells [PDF]

, 2007
Submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyIn light of the significant modulation of receptor activity previously shown by a peptide (designated L247), designed to mimic ...
D’Souza, Vijay Kenneth
core  

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Effects of single and combination dosage regimens of ketorolac and dexmedetomidine on allodynia and nociception in rat model of osteoarthritis: an animal multi-group trial

BMC Anesthesiology
Introduction Ketorolac is a non-steroidal anti-inflammatory drug (NSAID), commonly used for acute pain relief. Dexmedetomidine is a highly selective alpha-2-adrenergic receptor agonists with an analgesic effect.
Saeed Mohammad Taheri, Mona Khoramjouy, Noushin Nikray, Narjes Mohammadzadeh, Sona Eslampour, Ehsan Firoozi, Sepehr Roozdar, Seyed Mohammadreza Hashemian, Mehrdad Faizi   +8 more
doaj   +1 more source

Alpha-adrenergic regulation of secretion by tracheal glands

, 1990
The purpose of the present study was to begin to characterize, pharmacologically, the alpha-adrenergic regulation of glycoconjugate secretion from airway glands.
M. G. Marin, R. K. McBride, D. J. Culp, L. A. Graham   +3 more
core   +1 more source