Results 111 to 120 of about 101,334 (285)

Effect of intraoperative Dexmedetomidine infusion on Sevoflurane requirement and blood glucose levels during entropy-guided general anesthesia

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2014
Background: Dexmedetomidine has been shown to blunt the stress response to surgery. Hence a study was designed to evaluate the effect of intravenous (IV) Dexmedetomidine infusion during general anesthesia for abdominal surgeries on blood glucose levels ...
S S Harsoor   +4 more
doaj   +1 more source

Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]

open access: yes, 2016
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio   +4 more
core   +1 more source

Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi   +8 more
wiley   +1 more source

Spinal Tolerance and Dependence: Some Observations on the Role of Spinal N-Methyl-D-Aspartate Receptors and Phosphorylation in the Loss of Opioid Analgesic Responses

open access: yesPain Research and Management, 2000
The continuous delivery of opiates can lead to a reduction in analgesic effects. In humans, as in other animals, some component of this change in sensitivity seems likely to have a strong pharmacodynamic component.
Tony L Yaksh, Xiao-Ying Hua
doaj   +1 more source

Rabbit models of heart disease. [PDF]

open access: yes, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

Influence of Epinephrine and Medetomidine on Systemic Absorption of Lidocaine Applied Epidurally in Anesthetized Swine

open access: yesActa Veterinaria, 2014
Epinephrine and alpha 2 agonist drugs are often used with epidural anesthesia to minimize local anesthetic systemic absorption, as well as to prolong the duration of the block. The aim of the current study was to determine by which extent epinephrine and
Marija Lipar   +8 more
doaj   +1 more source

A novel octopamine receptor with preferential expression in Drosophila mushroom bodies [PDF]

open access: yes, 1998
Octopamine is a neuromodulator that mediates diverse physiological processes in invertebrates. In some insects, such as honeybees and fruit flies, octopamine has been shown to be a major stimulator of adenylyl cyclase and to function in associative ...
Han, K-A, Millar, NS
core  

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Role of Selective α and β Adrenergic Receptor Mechanisms in Rat Jejunal Longitudinal Muscle Contractility [PDF]

open access: yes, 2018
Gut motility is modulated by adrenergic mechanisms. The aim of our study was to examine mechanisms of selective adrenergic receptors in rat jejunum. Spontaneous contractile activity of longitudinal muscle strips from rat jejunum was measured in 5-ml ...
Balsiger, Bruno   +4 more
core  

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