Results 111 to 120 of about 104,693 (298)

G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]

, 2015
Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF, Foldes, G, Harding, SE, Hellen, N, Jabbour, R   +4 more
core   +1 more source

Quality of domestic cat semen collected by urethral catheterization after the use of different alpha 2-adrenergic agonists [PDF]

, 2020
Mónica Madrigal‐Valverde, Rodrigo Freitas Bittencourt, Antonio DL Ribeiro Filho, Vivian Fernanda Barbosa, Catharina de Albuquerque Vieira, Elton Amorim Romão, Isabella B Carneiro, M.C. Azevedo, Gediendson Ribeiro de Araújo   +8 more
openalex   +1 more source

Bladder Function and Safety of Vibegron in Men With Overactive Bladder Receiving Treatment for Benign Prostatic Hyperplasia: Outcomes From the Phase 3 Randomized Controlled COURAGE Trial

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose Vibegron was associated with improvements in efficacy versus placebo and was well tolerated in men with overactive bladder (OAB) on pharmacotherapy for benign prostatic hyperplasia (BPH) in the COURAGE trial (NCT03902080). Additional safety, bladder function, and urodynamics data are provided.
Eric S. Rovner, Janet Owens‐Grillo, Elizabeth Thomas, Sender Herschorn, Kenneth M. Peters, David Staskin, Salim Mujais   +6 more
wiley   +1 more source

Layer-by-Layer Assembly of Polysaccharides and 6,10-Ionene for Separation of Nitrogen-Containing Pharmaceuticals and Their Enantiorecognition by Capillary Electrophoresis

Journal of Chemistry, 2015
Two silica capillaries modified layer-by-layer with 6,10-ionene and N-(3-sulfo-3-carboxy)-propionylchitosan (SCPC) and with 6,10-ionene and dextran sulfate (DS) were prepared and investigated.
Anna Ioutsi, Elena Shapovalova, Aleksandra Prokhorova, Oleg Shpigun   +3 more
doaj   +1 more source

The alpha 1-adrenergic agonist methoxamine and the "loop" diuretic frusemide reduce nasal potential difference [PDF]

, 1991
AM Wood, Anh Tuan Dinh‐Xuan, George Cremona, A Lockhart, TW Higenbottam   +4 more
openalex   +1 more source

Acaricidal activity of small molecule antagonists of the tick kinin receptor against Rhipicephalus microplus acaricide‐susceptible and resistant strains

Pest Management Science, EarlyView.
Two small molecules, SACC‐0039590 and SACC‐0428788, killed cattle fever tick, R. microplus, susceptible Deutch strain and pyrethroid resistant Arauquita strain larvae. SACC‐0039590 at 1 mM decreased the reproductive parameters of Deutch females. Abstract BACKGROUND Resistance to acaricides underscores the need for tick control alternatives.
Waleed M. Arafa, Kimberly H. Lohmeyer, Patricia V. Pietrantonio   +2 more
wiley   +1 more source

Spinal Tolerance and Dependence: Some Observations on the Role of Spinal N-Methyl-D-Aspartate Receptors and Phosphorylation in the Loss of Opioid Analgesic Responses

Pain Research and Management, 2000
The continuous delivery of opiates can lead to a reduction in analgesic effects. In humans, as in other animals, some component of this change in sensitivity seems likely to have a strong pharmacodynamic component.
Tony L Yaksh, Xiao-Ying Hua
doaj   +1 more source

Effect of intraoperative Dexmedetomidine infusion on Sevoflurane requirement and blood glucose levels during entropy-guided general anesthesia

Journal of Anaesthesiology Clinical Pharmacology, 2014
Background: Dexmedetomidine has been shown to blunt the stress response to surgery. Hence a study was designed to evaluate the effect of intravenous (IV) Dexmedetomidine infusion during general anesthesia for abdominal surgeries on blood glucose levels ...
S S Harsoor, D Devika Rani, S Lathashree, S S Nethra, K Sudheesh   +4 more
doaj   +1 more source

Practice Guideline Recommendations Summary: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders [PDF]

, 2019
Objective To make recommendations on the assessment and management of tics in people with Tourette syndrome and chronic tic disorders. Methods A multidisciplinary panel consisting of 9 physicians, 2 psychologists, and 2 patient representatives ...
Cavanna, Andrea E., Holler-Managan, Yolanda, Jankovic, Joseph, Jarvie, Elizabeth, Martino, Davide, Muller-Vahl, Kirsten, Okun, Michael S., Oskoui, Maryam, Piacentini, John, Pringsheim, Tamara, Robinson, Michael, Roessner, Veit, Woods, Douglas W.   +12 more
core   +2 more sources

Effect of ‘combing’ on intramuscular sedation in pigs in a clinical setting—A randomised trial

Veterinary Record, EarlyView.
Abstract Background Pigs pose distinct challenges to the anaesthetist due to their temperament, the limitations of manual restraint and species‐specific anatomical features. Despite the importance of minimising stress during clinical procedures, gentle handling techniques tailored for pigs in a clinical setting have yet to be clearly described or ...
Kaitlynn C. Ban, Carolina H. Ricco Pereira, Kirk A. Muñoz, Chiara E. Hampton, Gianluca Bini, Phillip Lerche   +5 more
wiley   +1 more source