Results 121 to 130 of about 21,470 (209)

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

Rhinoscopy in horses: Endoscopic anatomy, technique and equipment

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page 481-488, September 2026.
Summary Rhinoscopy is a valuable imaging modality for diagnosis of conditions affecting the nasal and paranasal cavities in horses. Despite wide application in clinical practice, systematic endoscopic evaluation of the conchal bullae, nasal conchae and adjacent structures has seldom been described.
J. W. C. Lopes   +6 more
wiley   +1 more source

Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1390-1395, September 2026.
Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno   +6 more
wiley   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

open access: yesJournal of Anatomy, Volume 249, Issue 3, Page 565-577, September 2026.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou   +6 more
wiley   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga   +4 more
wiley   +1 more source

Spinal motoneuron excitability is homeostatically regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice. [PDF]

open access: yesProg Neurobiol
Antonucci S   +14 more
europepmc   +1 more source

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through In Situ Differentiation and Morphogenesis of iPSCs

open access: yesAdvanced Science, Volume 13, Issue 45, 13 August 2026.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick   +8 more
wiley   +1 more source

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