Results 111 to 120 of about 31,393 (254)

A expressão da proteína Fos após injeção intracerebroventricular de adrenalina em ratos saciados [PDF]

, 2014
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014Estudos prévios em nosso laboratório sugerem que a injeção de adrenalina (AD) no núcleo mediano
Flores, Rafael Appel
core  

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Additional file 10: of Effects of perioperative goal-directed fluid therapy combined with the application of alpha-1 adrenergic agonists on postoperative outcomes: a systematic review and meta-analysis

, 2018
Forest plot comparing overall complication rates for patients receiving GDFT combined with alpha-1 adrenergic agonists versus control, divided by (a) age of patients: patients aged
Shuai Feng (346540), Wei Xiao (16583), Xue Wang (102830), Kun Yang (19445), Shuyi Yang (5642801), Tianlong Wang (794339)   +5 more
core   +1 more source

Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and Addiction

Biomolecules
Recent bioassay studies have unexpectedly supported the high (computationally predicted) binding affinities of angiotensin receptor blockers (ARBs) at α-adrenergic receptors (αARs) in isolated smooth muscle.
Harry Ridgway, Graham J. Moore, Laura Kate Gadanec, John M. Matsoukas   +3 more
doaj   +1 more source

Layer-by-Layer Assembly of Polysaccharides and 6,10-Ionene for Separation of Nitrogen-Containing Pharmaceuticals and Their Enantiorecognition by Capillary Electrophoresis

Journal of Chemistry, 2015
Two silica capillaries modified layer-by-layer with 6,10-ionene and N-(3-sulfo-3-carboxy)-propionylchitosan (SCPC) and with 6,10-ionene and dextran sulfate (DS) were prepared and investigated.
Anna Ioutsi, Elena Shapovalova, Aleksandra Prokhorova, Oleg Shpigun   +3 more
doaj   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Activation of alpha-adrenergic response in tracheal smooth muscle: a postreceptor mechanism

, 1983
We have investigated the activation of alpha-adrenergic contractile responses in dog tracheal smooth muscle. After cholinergic and beta-adrenergic blockade, neither electrical field stimulation nor alpha-adrenergic agonists caused contraction of ...
B. E. Skoogh, J. K. Brown, P. J. Barnes, J. A. Nadel   +3 more
core   +1 more source

Study of the selectivity of alpha(1)-adrenergic antagonists by molecular modeling of alpha(1a)-, alpha(1b)-, and alpha(1d)-adrenergic receptor subtypes and docking simulations

, 2013
Modeling of alpha(1a), alpha(1b), and alpha(1d) adrenergic receptor subtypes has been performed using InsightII software and bovine rhodopsin as a template.
Agbaba, Danica, Eric, Slavica, Zloh, Mire, Solmajer, Tom, Kotnik, Miha   +4 more
core   +2 more sources

Effects of protein concentration and beta-adrenergic agonists on ruminal bacterial communities in finishing beef heifers.

PLoS ONE
To improve animal performance and modify growth by increasing lean tissue accretion, beef cattle production has relied on use of growth promoting technologies such as beta-adrenergic agonists.
Alison P Pfau, Madison T Henniger, Kendall L Samuelson, Kristin E Hales, Clint A Löest, Mike E Hubbert, Amanda K Lindholm-Perry, Amanda M Egert-McLean, Katie M Mason, Elizabeth A Shepherd, Brynn H Voy, Phillip R Myer   +11 more
doaj   +1 more source

Spinal Tolerance and Dependence: Some Observations on the Role of Spinal N-Methyl-D-Aspartate Receptors and Phosphorylation in the Loss of Opioid Analgesic Responses

Pain Research and Management, 2000
The continuous delivery of opiates can lead to a reduction in analgesic effects. In humans, as in other animals, some component of this change in sensitivity seems likely to have a strong pharmacodynamic component.
Tony L Yaksh, Xiao-Ying Hua
doaj   +1 more source