Results 11 to 20 of about 93,467 (314)
Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]
The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Andersson, Karl-Erik +10 more
core +15 more sources
Aims: To assess the efficacy in lowering post-operative urinary retention, urinary tract infection and lower urinary tract symptoms and the incidence of adverse events among 12 interventions and to perform risk–benefit analysis.
Pokket Sirisreetreerux +5 more
doaj +1 more source
Preventive effects of tamsulosin for postoperative urinary retention after lower limb arthroplasty: A randomized controlled study [PDF]
Purpose: This prospective, randomized, controlled study investigated the use of tamsulosin, a selective alpha-blocker, as a prophylactic medication to prevent postoperative urinary retention (POUR) following lower limb arthroplasty.
Chang Il Choi +5 more
doaj +1 more source
The Noradrenergic System is Partly Involved in Resveratrol Antidepressant and Anti-Obsessive Like Effects in Mice Model [PDF]
Background and objectives: Resveratrol is a natural phenol in food particularly the skin of fruits like red grapes. It has shown biological, and antidepressant effects.
Azadeh Mesripour*, Fatemeh Payandekhah
doaj +1 more source
A Prospective, Multicenter, Open-Label Study of Dose Escalation Therapy in Male Patients With Nocturia Refractory to 0.2-mg Tamsulosin Monotherapy [PDF]
Purpose To investigate the efficacy and safety of 0.4 mg of tamsulosin in patients with nocturia not responding to 0.2 mg. Methods Patients with intractable nocturia after treatment with 0.2 mg of tamsulosin for>1 month were included in a multicenter ...
Ho Song Yu +4 more
doaj +1 more source
Effects of Alpha‐ and Beta‐Adrenergic Agonists and Antagonists on Growth Hormone Secretion in Man [PDF]
Ezio Ghigo +7 more
openalex +2 more sources
Obesity is widely reported to be associated with a higher risk of the severity and worse clinical outcome of COVID-19. With the global prevalence of obesity, exploring the relationship between obesity and the severity of COVID-19 disease is of major ...
Auda Fares +3 more
doaj +1 more source
Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms [PDF]
Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old.
Yeon Joo Kim, Bum Sik Tae, Jae Hyun Bae
doaj +1 more source
Effective therapies for coronavirus disease 2019 (COVID-19) are urgently needed, and pre-clinical data suggest alpha-1 adrenergic receptor antagonists (α1-AR antagonists) may be effective in reducing mortality related to hyperinflammation independent of ...
Liam Rose +17 more
doaj +1 more source

